Sodium tolmetin dihydrate supplier

Name
Sodium tolmetin dihydrate
EINECS 252-687-3
CAS No. 64490-92-2
Density
Solubility Soluble in water
Melting Point 155-157 (dec.)
Formula C₁₅H₁₄NNaO₃^.2H₂O
Boiling Point 483.2°C at 760 mmHg
Molecular Weight 315.30
Flash Point 246°C
Transport Information
Appearance crystalline solid
Safety 36
Risk Codes 22-38
Molecular Structure
Hazard Symbols Xn
Synonyms 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, dihydrate (9CI);1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, hydrate (1:1:2);Tolmetin sodium;Tolumetin sodium dihydrate;1-Methyl-5-(p-toluoyl)pyrrole-2-acetic acid sodium salt dihydrate;
PSA 80.59000
LogP 0.72830

Sodium tolmetin dihydrate Specification

The Sodium tolmetin dihydrate, with the CAS registry number 64490-92-2, is also known as 1-Methyl-5-(p-toluoyl)pyrrole-2-acetic acid sodium salt dihydrate. It belongs to the product categories of API intermediates; Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals. This chemical's molecular formula is C₁₅H₁₄NNaO₃^.2H₂O and molecular weight is 315.30. What's more, its systematic name is Sodium [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetate hydrate (1:1:2). Its classification codes are: (1)Anti-inflammatory; (2)Drug / Therapeutic Agent; (3)Reproductive Effect. This chemical has been used as anti-inflammatory.

Physical properties of Sodium tolmetin dihydrate are: (1)#H bond acceptors: 6; (2)#H bond donors: 5; (3)#Freely Rotating Bonds: 4; (4)Polar Surface Area: 80.59 Å².

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful if swallowed and is irritating to skin. When using it, you need to wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].O=C([O-])Cc2ccc(C(=O)c1ccc(cc1)C)n2C.O.O
(2)Std. InChI: InChI=1S/C15H15NO3.Na.2H2O/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18;;;/h3-8H,9H2,1-2H3,(H,17,18);;2*1H2/q;+1;;/p-1
(3)Std. InChIKey: QQILXENAYPUNEA-UHFFFAOYSA-M

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	550mg/kg (550mg/kg)		European Patent Application. Vol. #134763.
mouse	LD50	intravenous	> 622mg/kg (622mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
mouse	LD50	oral	899mg/kg (899mg/kg)		European Patent Application. Vol. #134763,
mouse	LD50	subcutaneous	670mg/kg (670mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
rat	LD50	intraperitoneal	612mg/kg (612mg/kg)		European Patent Application. Vol. #134763.
rat	LD50	intravenous	> 724mg/kg (724mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
rat	LD50	oral	914mg/kg (914mg/kg)		European Patent Application. Vol. #134763.
rat	LD50	subcutaneous	1050mg/kg (1050mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.

Product Name

Sodium tolmetin dihydrate

Sodium tolmetin dihydrate Specification

Related Products

Hot Products