Solvent Yellow 33

Reported in EPA TSCA Inventory.

The C.I. Solvent yellow 33 with CAS registry number of 8003-22-3 is also known as 2-(2-Quinolinyl)-1H-indene-1,3(2H)-dione. The IUPAC name is 2-Quinolin-2-ylindene-1,3-dione. It belongs to product categories of Solvent Dyestuff . Its EINECS registry number is 232-318-2. In addition, the formula is C₁₈H₁₁NO₂ and the molecular weight is 273.29. This chemical is a yellow powder and should be stored in cool and dry place.

Physical properties about C.I. Solvent yellow 33 are: (1)ACD/LogP: 3.16; (2)ACD/LogD (pH 5.5): 0.67; (3)ACD/LogD (pH 7.4): 0.67; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 4.02; (7)ACD/KOC (pH 7.4): 4.02; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 1; (10)Index of Refraction: 1.706; (11)Molar Refractivity: 79.06 cm³; (12)Molar Volume: 203 cm³; (13)Surface Tension: 64.3 dyne/cm; (14)Density: 1.345 g/cm³; (15)Flash Point: 260 °C; (16)Enthalpy of Vaporization: 78.62 kJ/mol; (17)Boiling Point: 514.5 °C at 760 mmHg; (18)Vapour Pressure: 1.07E-10 mmHg at 25 °C.

Preparation of C.I. Solvent yellow 33: it is prepared by reaction of 2-methyl-quinoline with phthalic acid anhydride. The reaction occurs at 180 °C for 30 minutes. The yield is about 53.6%.

Uses of C.I. Solvent yellow 33. It is used in spirit lacquers, polystyrene, polycarbonates, polyamides, acrylic resins, and to color hydrocarbon solvents. It is also used in externally applied drugs and cosmetics.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. It is harmful if swallowed. During using it, wear suitable protective clothing, gloves and eye/face protection. Avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: C1=CC=C2C(=C1)C=CC(=N2)C3C(=O)C4=CC=CC=C4C3=O
2. InChI: InChI=1S/C18H11NO2/c20-17-12-6-2-3-7-13(12)18(21)16(17)15-10-9-11-5-1-4-8-14(11)19-15/h1-10,16H
3. InChIKey: IZMJMCDDWKSTTK-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rabbit	LD50	skin	> 2gm/kg (2000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,
rat	LDLo	oral	5gm/kg (5000mg/kg)	GASTROINTESTINAL: OTHER CHANGES	Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,