Eschenmoser's salt Dimethylformiminium chloride CAS#30354-18-8
It is an environmental friendly reagent, provides outstanding performance by improving the yielding rate of many Mannich reactions which is hard to occur under normal conditions. It is especially effective for ketones with large steric hindrance and asymmetrical ketones on atoms with high substituent group.
Synonyms
Eschenmoser's salt;
Dimethylformiminium chloride;
Methylenedimethylammonium chloride
It is an environmental friendly reagent, provides outstanding performance by improving the yielding rate of many Mannich reactions which is hard to occur under normal conditions. It is especially effective for ketones with large steric hindrance and asymmetrical ketones on atoms with high substituent group. For this reason, it is widely used in the synthesize of drugs and intermediates.
- Pain-killer and Sedatives: Tramadol Hydrochloride intermediate “2-dimethylamine methylcyclohexanone”.
- Antemetic: Ondansetron hydrochloride intermediate “1,2,3,9-9 methyl-3- dimethylaminomethyl-4-H-carbazole-4-ketone”
- Cymbalta Hydrochloride intermediate “1,2,3-dimethylamino-1-(2-thienyl)-1-acetone hydrochloride”
- Bactericide, drugs for peptic ulcer: Ranitidine Hydrochloride intermediate “5-(dimethylamino) methyl-furancarbinol”
- Donaxine, Edema inhibitor, Hypotensor, Anticancer drugs
- Antivirus : Arbidol Hydrochloride,
- Liver-protective drugs, Reactive dyestuff, Synthesized spices, etc.
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