Tetramethylpyrazine...

Tetramethylpyrazine / Ligustrazine Phosphate CAS NO. 1124-11-4

Tetramethylpyrazine / Ligustrazine Phosphate CAS NO. 1124-11-4

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Keywords

Tetramethylpyrazine Ligustrazine Phosphate CAS 1124-11-4

Quick Details

  • Appearance:White or off-white crystalline powder. Has the tasty of heating beef and lard and the flavor of fermentative soybean, and will show the milk and chocolate flavor when dilute to 20mg/kg
  • Application:1. Anticoagulant, is used for treat of Occlusive Cerebrovascular Disease.
  • PackAge:25KG / Paper Barrel
  • ProductionCapacity:5|Metric Ton|Month
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Ligustrazine Phosphate Tetramethylpyrazine CAS 1124-11-4

sinoprochem

Specification
  Tetramethylpyrazine / Ligustrazine Phosphate Information
  Tetramethylpyrazine / Ligustrazine Phosphate Basic Information
Product Name Tetramethylpyrazine / Ligustrazine Phosphate
Synonyms

BS Factor; Ligustrazine; Pyrazine,tetramethyl-; Tetramethylpyrazin; tetramethyl-pyrazin; 2,3,5,6-TETRAMETHYLPYRAZINE; 2,3,5,6-TETRAMETHYLPYRAZINES; 2,3,5,6-TETRAMETHYL-1,4-PYRAZINE

CAS RN 1124-11-4
EINECS 214-391-2
Molecular Formula (MF) C8H12N2
Formula Weight (MW) 250.2
Related Classes Medicinal herb components; Pyrazine;Heterocyclic Compounds; Pyrazines; pyrazine; Mono- & Polyalkylpyrazines; pyrazine Flavor; meat flavor; essence and perfume; Alphabetical Listings; Flavors and Fragrances; Q-Z; Certified Natural Products Flavors and Fragrances; Building Blocks; Heterocyclic Building Blocks; Food Additives; flavouring (flavor enhancer); Indentical flavor and synthetic perfume; pyrazines; Building Blocks; Chemical Synthesis; Heterocyclic Building Blocks;  reference substance of traditional Chinese medicine; standard; reference substance, standard; fragrance and flavor; plant extracts; chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract; reference substance
Mol File 1124-11-4.mol
--1124-11-4
  Tetramethylpyrazine / Ligustrazine Phosphate Chemical Properties
Chemical Properties Apprance: White or off-white crystalline powder. Has the tasty of heating beef and lard and the flavor of fermentative soybean, and will show the milk and chocolate flavor when dilute to 20mg/kg.
Melting Point (MP):  173-177℃
Boiling Point: 190 °C (lit.)
FEMA: 3237

Flash Point: 128-130°C/200mm

BRN: 113100  

Moisture: ————

Purity:————

Density: 1.08g/cm2

Solubility: Dissolving in the water.

Stability: Stable. Incompatible with strong acids, strong oxidizing agents.

NIST: Pyrazine, tetramethyl-(1124-11-4)   

EPA: Pyrazine, tetramethyl-(1124-11-4)  

  Tetramethylpyrazine / Ligustrazine Phosphate Safety Information
Hazard Codes Xn, Xi
Risk Statements  22-37/38-41-36/37/38
Safety Statements  26-39-24/25-37/39-36  
RTECS UQ3905000
HS Code 29339990
WGK Germany 3
  Tetramethylpyrazine / Ligustrazine Phosphate Usage and Synthesis
Usage

1. Anticoagulant, is used for treat of Occlusive Cerebrovascular Disease.

2. Anti-platelet aggregation, arteriectasia, and improve microcirculation and promoting blood circulation and removing blood stasis. With the depolymerization effect for the aggregation of platelet. 

3. GB 2760—1996: Be available in flavouring. Mainly used to compound essence with meat and cocoa, peanut, nut, coffee, chocolate. 

4.Used to drug production.

5.Used to condiment, enhanced sweeteners within alcoholic beverage, flavoring agents and supplement within the cigarette.

  Production Methods

1. 2,3-Butanedione monoxime is made from butanone and ethyl nitrite by condensation, then reductive ring closure to get methylpyrazine. The product of cyclization reaction to proceed thesteam distillation, which distillation cooled, crystallise, filter, get tetramethylpyrazine crude product. When purification need to useWater repetition crystallization and activated carbon decoloration. When prepare hydrochloride, which can add dropwise ethanol solution contains 15%-20% hydrogen chloride in the acetone to make salt.

2. Be made from 2, 3-butanedione and 2, 3- butanediamine condensation.

  Tetramethylpyrazine / Ligustrazine Phosphate Package
Package Paper Barrel: 25KG / Paper Barrel  
Month Output  5 Tons / Month
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 CAS 1124-11-4

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We manufacture pharmaceutical inter-mediate conforming to --GMP (Good Manufacturing Practices) standards.

 

Our efficient and systematic manufacturing facility and effective supply chain system ensures quickly send within 30 days of confirmation of the order.

We offer products with customized packing and various suture-needle combination as required by the customer.

 

We manufacture and supply 56-95-1, 3697-42-5, 18472-51-0, 20880-92-6, 1124-11-4, 76494-51-4, 118-29-6 as per the customer requirements.

 

Package

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About Sinoprochem Company

SinoProChem Factory

Sinoprochem was founded in 2010 and is located in Development Zone, Heze, Shandong Province, China.
With an occupied floor area of 5,500 square meters workshop, the company has abundant financial resources and advanced equipment, including Gas / Liquid Chromatography, Halogen Moisture Meter, Spectrophotometer, Polarimeter and so on.

 

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