Daptomycin Cidecin Ly-146032
Product name | Daptomycin |
CAS NO. | 103060-53-3 |
Synonyms | Daptomycin |
Category | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals. |
Standard | purity:>99% |
Appearance | Daptomycin powder |
Shelf life | 2 years |
Usage |
Daptomycin is used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. |
Storage | Daptomycin should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Daptomycin is a lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms. As a calcium-dependent antibiotic, Daptomycin has been reported to act on the cytoplasmic membrane and undergo a conformational change upon interaction with lipid membranes in a model system. After the conformational change occurs, the compound is inserted into the membrane and causes significant perturbations. Membrane depolarization and leakage occurs, causing death in susceptible organisms.
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