intermediate of LCZ...

intermediate of LCZ696

intermediate of LCZ696

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: >98% Pharma Grade
  • Payment Terms : L/C,D/A,D/P

Keywords

4-(((2R,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-Methyl-5-oxopentan-2-yl)aMino)-4-oxobutanoic high quality AHU-377 Sacubitril in stock AHU-377 good China supplier

Quick Details

  • Appearance:
  • Application:intermediate of LCZ696
  • PackAge:Pack in paper-drums and two plastic-bags inside. 25.00 kg/Drum
  • ProductionCapacity:100|Kilogram|Month
  • Storage:Store in a well-closed place with room temperature and no direct sun light.
  • Transportation:By sea; By air;by courier

Superiority:

1,8 years exporting experience;
2.Competitive price and quality;
3,Free sample can be provided;
4,We are sincerely responsible for the"sample quality" , "product quality" and "After Service";

5. prompt delivery;

6.Packed well

7.“High-quality products, cost-effective prices, best reputation and professional services” is the managing motto of our company.

8.We are insisting and striving ……
Just for our promise:
“EnBridge will do our best to be better”
 

Details:

Quick Details

 

CAS No.:
149709-62-6
 Other Names:
AHU-377
 MF:
C24H29NO5 C4H11NO3
EINECS No.:
N/A
 Place of Origin:
Jiangsu, China (Mainland)
 Type:
Cardiovascular Agents
Grade Standard: Industrial Grade Brand Name: Enbridge Model Number:
API
Purity:
99%

Packaging & Delivery

Packaging Details: For small quantity: Bag
Commercial quantity: fiber drum
Delivery Detail: Negotiable

     

 

 

Product Description

1 Basic information

 

HP90699 AHU-377 (Sacubitril)   149709-62-6
AHU-377 (Sacubitril)   149709-62-6    
MF C24H29NO5  C4H11NO3 MSDS:Aviable
MW 532.6 Place of Origin:China
Synonym: Sacubitril
AHU-377 (Sacubitril) Description AHU-377 (Sacubitril) is a prodrug which is activated in vivo by hydrolytic enzyme esterases to form an active compound LBQ657 that selectively and potently inhibits the enzyme Neprilysin with Ki at low nM. Neprilysin is a protease responsible for the degradation of atrial and brain natriuretic peptides. Inhibition of the enzyme prevents the degradation of natriuretic peptides and activates cGMP signaling pathways that regulate volume and blood pressure. AHU-377 (Sacubitril) is an investigational antihypertensive drug being studied for use in combination with Valsartan (molar ratio: 1:1) (Our Prod No. CT-VALS). The combination drug, known as LCZ696, is in clinical trials for the treatment of heart failure.
AHU-377 (Sacubitril) Structual
                       
Purity 99% min
AHU-377 (Sacubitril) Storage condition Store at 0°C (short term), -20°C (long term)  desiccated
  AHU-377 Documents provide  

Enbridge PharmTech Co., Ltd. is an innovative company integrated with R&D, manufacturing, marketing and distribution of intermediates and fine chemicals, mainly used to pharmaceutical, pesticide, cosmetics, health care products and electronic chemicals. Our core services also include Custom Synthesis and Contract Manufacturing Services.
Enbridge PharmTech has one R&D center and two manufacturing bases. R&D center is equipped with good organic synthesis and analytical instrumenets. In our two production bases, we have large-scale reactors which cover various SS/ Glass Lined reactors capable of conducting high pressure, high temperature and low temperature reactions. We have a large number of well-equiped instruments and have the production capability from kilogram to ton...Pharma Grade
 

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