CasNo.53123-88-9,GMP certified Rapamycin / Sirolimus with DMF /FDA ,(53123-88-9) Suppliers

10 Gram	Negotiable

Min.Order :10 Gram
Purity: 99% up
Payment Terms : L/C,T/T

Keywords

Rapamycin 53123-88-9 Sirolimus

Quick Details

Appearance:white powder
Application:Rapamycin is a triene macrolide antibiotic, which demonstratesanti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and pro
PackAge:foil bag
ProductionCapacity:5000|Gram|Year
Storage:
Transportation:

Superiority:

Quick details of Rapamycin ( Sirolimus ):

Product name: Rapamycin

Other name: Sirolimus

CAS No: 53123-88-9

Molecular Formula : C51H79NO13

Molecular Weight: : 914.18

Appearance: off-white to yellow crystalline powder

Purity: 99% min

Our advantage for Rapamycin:

1) Output 5kgs/year , 500g in stock

2) Good quality ,high purity 99% up ,competitive price ,

3) with GMP /DMF documents

4) Quick delivery by courier (FedEx ,EMS ) in 3days after your payment

5) Provide free sample for testing before order

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 37 years.

2) ISO 9001:2015 & SGS audited supplier .

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Details:

COA of Rapamycin / Sirolimus :

Item	Specifications	Results
Description	off-white to yellow crystalline powder	Complies
Identification	The IR spectrum of Potassium Bromide preparation of the sample exhibits maxima at the same wavelengths as that of a similar preparation of in-house reference standard	Complies
	The UV spectrum of 95% Ethanol preparation of the sample exhibits maxima at 267nm, 277nm, 288nm that of similar preparation of in-house reference standard.	Complies
	The retention times of the peaks for the Trans- and Cis-stereoisomers in the chromatogram of Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the Assay	Complies
Loss on drying	≤0.5%	0.16%
Heavy metal	≤0.002%	Complies
Total impurity	≤2.0%	0.76%
Single impurity	≤1.0%	0.67%
Cis-stereoisomer of Sirolimus	≤5.0%	2.4%
Assay	≥98.0%	99.2%
Conclusion	The production complies with enterprise standard

3. Application of Rapamycin / Sirolimus :

Rapamycin is a triene macrolide antibiotic, which demonstrates

anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins. Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.