Polyethylene-polypropylene glycol BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL Tergitol (TM) L-81
Type |
Appearance (25°C) |
Mol wt |
Cloud point (1% solution) (°C) |
pH |
HLB |
Pluronic L 31 |
Colorless liquid |
1100 |
—— |
5.0~7.0 |
3.5 |
Pluronic P 35 |
White cream |
1900 |
70~85 |
5.0~7.0 |
18.5 |
Pluronic F 38 |
White solid |
5000 |
>100 |
5.0~7.0 |
30 |
Pluronic L 42 |
Colorless liquid |
1630 |
37 |
5.0~7.0 |
8 |
Pluronic L 43 |
Colorless liquid |
1850 |
42 |
5.0~7.0 |
10 |
Pluronic L 44 |
Colorless liquid |
2200 |
45~55 |
5.0~7.0 |
12 |
Pluronic L 61 |
Colorless liquid |
2000 |
17~21 |
5.0~7.0 |
3 |
Pluronic L 62 |
Colorless liquid |
2500 |
21~26 |
5.0~7.0 |
7 |
Pluronic L 63 |
Colorless liquid |
2650 |
34 |
5.0~7.0 |
11 |
Pluronic L 64 |
Colorless liquid |
2900 |
57~61 |
5.0~7.0 |
13 |
Pluronic P 65 |
White cream |
3500 |
75~85 |
5.0~7.0 |
15 |
Pluronic F 68 |
White flake |
8350 |
≥95 |
5.0~7.0 |
29 |
Test Method |
—— |
GB/T 6368 |
GB/T 5559 |
GB/T 6368 |
Reference |
F-127 gel can be used as carrier for controlling and realsing anticancer drug, for medicine applied to rectum for diminishing inflammation and relieving pain. Iit is also used for the controlled and released medicine which is applied to the mucosa of navity and vagina.
F-68 can be used as defoaming agent for blood circulation in the artificial heart-lung machine in order to prevent the air from entering the blood of the patient,decrease the formation of formation of foam and increase oxygenation. In LIPOMUL(manufactured by Upjohn Corp. of America), as an emusifier, it is used , in combination with soya phophatide, for preparing fat emulsion infusion for intravenous injection. In the production of solid dispersion medicine, as a carrier, it can greatly enhance the rate of dissolving out and biological utilization of the medicine. It is relatively ideal quick-acting carrier for solid dispersion.
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