HS-173

HS-173

HS-173

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99%

Keywords

HS-173 1276110-06-5 99% HS-173

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  • Application:1276110-06-5
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  • ProductionCapacity:100g|Metric Ton|Day
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Details:

HS-173 shows potent antiproliferative effects in T47D, SK-BR3, and MCF7 cells with IC50 of 0.6, 1.5, and 7.8 μM, respectively. HS-173 causes complete suppression of the PI3K pathway in cancer cell lines (Hep3B and SkBr3). Moreover, HS-173 induces cell apoptosis by affecting cell-cycle distribution and activating caspases, and block VEGF-induced angiogenesis in vitro. Combined treatment with Sorafenib and HS-173 has a synergistic anti-cancer effect on pancreatic cancer cells

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