RGFP966 1396841-57-8 98% RGFP966
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A titration of RGFP966 showed that at 5-10 ?M there was only a modest affect on H3K56ac, which was approximately 15-fold less than found with Depsipeptide. Treatment of two CTCL cell lines, HH and Hut78, with the HDAC3-selective inhibitors 966 and 136, for 24 hours prior to western blot analysis resulted in increased acetylation at H3K9/K14, H3K27, and H4K5, but not H3K56ac (even at 10?M)
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