ANA-12

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1 Gram	Negotiable

1 Gram

Negotiable

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Min.Order :1 Gram
Purity: 99%

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ANA-12 219766-25-3 99% ANA-12

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Application:219766-25-3
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ProductionCapacity:100g|Metric Ton|Day
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ANA-12 prevented activation of the receptor by BDNF with a high potency. ANA-12 showed direct and selective binding to TrkB and inhibited processes downstream of TrkB without altering TrkA and TrkC functions. Saturation binding studies with TrkBECD-Fc showed that ANA-12 binds TrkBECD-Fc with a Kd of 12 μM . The selective TrkB (tropomyosin-receptor-kinase) antagonist ANA-12 reduced OIH when given one or seven days after cessation of morphine.

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