Acetamide, N-[4-cyano-2-(trifluoromethyl)phenyl]-

Superiority:

This chemical is called Acetamide, N-[4-cyano-2-(trifluoromethyl)phenyl]-, and its systematic name is N-[4-cyano-2-(trifluoromethyl)phenyl]acetamide. With the molecular formula of C₁₀H₇F₃N₂O, its molecular weight is 228.17. The CAS registry number of this chemical is 175277-96-0. Additionally, its product categories are Phenyls & Phenyl-Het.

Other characteristics of the Acetamide, N-[4-cyano-2-(trifluoromethyl)phenyl]- can be summarised as followings: (1)ACD/LogP: 1.58; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.58; (4)ACD/LogD (pH 7.4): 1.58; (5)ACD/BCF (pH 5.5): 9.36; (6)ACD/BCF (pH 7.4): 9.36; (7)ACD/KOC (pH 5.5): 172.54; (8)ACD/KOC (pH 7.4): 172.54; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 44.1 Å²; (13)Index of Refraction: 1.493; (14)Molar Refractivity: 49.33 cm³; (15)Molar Volume: 169.5 cm³; (16)Polarizability: 19.55×10^-24cm³; (17)Surface Tension: 40.1 dyne/cm; (18)Density: 1.34 g/cm³; (19)Flash Point: 177.3 °C; (20)Enthalpy of Vaporization: 61.64 kJ/mol; (21)Boiling Point: 369.6 °C at 760 mmHg; (22)Vapour Pressure: 1.17E-05 mmHg at 25°C.

Production method of this chemical: The Acetamide, N-[4-cyano-2-(trifluoromethyl)phenyl]- could be obtained by the reactants of hydrogen cyanide; copper(1+) salt and 4'-iodo-2'-trifluoromethyl-acetanilide. This reaction needs the solvent of hexamethylphosphoric acid triamide. The yield is 71 %. In addition, this reaction should be taken for 3 hours at the temperature of 150°C.