4-Acetamidobenzonitrile

Superiority:

The Acetamide,N-(4-cyanophenyl)-, with the CAS registry number 35704-19-9 and EINECS registry number 252-685-2, has the systematic name and IUPAC name of N-(4-cyanophenyl)acetamide. It is a kind of off-white crystalline powder and chunks, and belongs to following the product categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts. And the molecular formula of the chemical is C₉H₈N₂O.

The characteristics of Acetamide,N-(4-cyanophenyl)- are as followings: (1)ACD/LogP: 1.37; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.37; (4)ACD/LogD (pH 7.4): 1.37; (5)ACD/BCF (pH 5.5): 6.46; (6)ACD/BCF (pH 7.4): 6.46; (7)ACD/KOC (pH 5.5): 132.38; (8)ACD/KOC (pH 7.4): 132.38; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 44.1 Ų; (13)Index of Refraction: 1.557; (14)Molar Refractivity: 44.34 cm³; (15)Molar Volume: 137.7 cm³; (16)Polarizability: 17.57×10^-24cm³; (17)Surface Tension: 49.2 dyne/cm; (18)Density: 1.16 g/cm³; (19)Flash Point: 191 °C; (20)Enthalpy of Vaporization: 64.18 kJ/mol; (21)Boiling Point: 392.1 °C at 760 mmHg; (22)Vapour Pressure: 2.34E-06 mmHg at 25°C. 

Preparation of Acetamide,N-(4-cyanophenyl)-: This chemical can be prepared by acetic acid anhydride and 4-amino-benzonitrile. The reaction will need the menstruum acetic acid and heating. The reaction time is 15 minutes. 

Uses of Acetamide,N-(4-cyanophenyl)-: It can react with 2-methoxy-ethanol to produce 2-methoxyethyl 4-acetylaminobenzimidate hydrochloride. This reaction will need reagent HCl, and the yield is about 67%.