D-Isovaline

D-Isovaline

D-Isovaline

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: 99%min
  • Payment Terms : L/C,T/T

Keywords

D-Isovaline

Quick Details

  • Appearance:White needles or crystalline powder
  • Application:Organic synthesis
  • PackAge:as your request
  • ProductionCapacity:|Metric Ton|Day
  • Storage:store in dry and cool place
  • Transportation:by air or by sea

Superiority:

1、What we have 
We have a modern manufacturing facility in China. The website photos are real factory
2、What we can do 
Our strong R&D capability means we can develop new products besd on your requirements.
3、Who we serve 
Our diversified customers are range from small business to global fortune 500 companies like MITSUBISHI

Details:

Isovaline is a rare amino acid transported to earth by the Murchison meteorite, which landed in Australia in 1969. The discovery of isovaline in the biosphere demonstrates an extraterrestrial origin of amino acids and has been linked to the homochirality of life on earth suggesting a role in the origin of life.

The structure of isovaline is similar to the amino acids GABA and glycine, the chief inhibitory neurotransmitters in the mammalian central nervous system. Isovaline acts as an analgesic in mice by activating peripheral GABAB receptors.In a mouse model of osteoarthritis isovaline restored mobility, suggesting inhibition of nociception by isovaline in the synovial membrane of the mouse knee.

Isovaline does not cross the blood-brain barrier and does not enter into the brain or spinal cord. Drugs such as opioids cross the blood-brain barrier to produce analgesia but often produce confusion, sedation and addiction.

Isovaline acts downstream to the cyclooxygenase system that NSAIDs inhibit, suggesting a means to avoid adverse effects such as irritation of the gastrointestinal system.

This novel first-in-class compound has potential for treatment of acute and chronic pain, without the negative side effects associated with other commonly used analgesics.

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