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1 Kilogram |
Negotiable |
Griseofulvin 126-07-8 GMP Griseofulvin
Product Name: Griseofulvin
Cas No.: 126-07-8
Molecular Formula: C17H17ClO6
Molecular Weight: 352.77
Griseofulvin is used to treat skin infections such as jock itch, athlete's foot, and ringworm; and fungal infections of the scalp, fingernails, and toenails.
Test items |
Specifications (BP2011 /EP7.0) |
Description |
A white or yellow white microfine powder |
Identification |
A: IR |
B:Colour test (a white-red colour develops) |
|
Acidity |
Not more than 1.0ml of 0.02M sodium hydroxide is required. |
Solubility |
Practically insoluble in water,freely soluble in dimethyl formamide and in tetrachloroethane,slightly soluble in ethanol and in methanol. |
Specific optical rotation |
Calculated with reference to the dried substance +354°~+364° |
Particle size |
95% no more than 5um(larger particles which may occasionally exceed 30um) |
Melting point |
It melts at about 220℃ |
Appearance of solution |
The solution is clear |
Not more intensely coloured than reference solution Y4 |
|
Related substances: |
|
Dechologriseofulvin |
Less than 0.60 |
Dehydrogriseofulvin |
Less than 0.15 |
Substances soluble in light petroleum |
NMT 0.20% |
Loss on drying |
NMT 1.00% |
Sulphated ash |
NMT 0.20% |
Abnormal toxicity |
Five mice orals,none of the mice dies within 48h |
Assay(anhydrous substance) |
97.0% to 102.0% |
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