Paclitaxel Taxus Chinensis Extract with Free Sample

English Name: Paclitaxel
Appearance: White crystalline powder
Specification: 99%
Solubility: Soluble in ethanol, dichloromethane, etc., slightly soluble in acetonitrile, etc. 
Melting Point: 230~233°C
Loss on drying: ≤0.5%
CAS No.: 33069-62-4
Molecular Formula: C47H51NO14
Molecular Weight: 853.92

 

Description
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. 

Main Function
1. Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer. 
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors. 
3. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma. 
4. Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; Locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents. 

Application: 
(1). As drugs raw materials of anti-cancer, it is mainly used in pharmaceutical field; 
(2). As active ingredients of products for preventing breast cancer, ovarian cancer and lung cancer, it is mainly used in health product industry. 


Storage: 
Stored in a cool&dry well-closed container, keep away from moisture and strong light/heat. 
Shelf life: 
Two years under well storage situation
Packing: 
Material: In fiber-drums with two-plastic bags inside. 
Wight: Net weight 25kg/drum; Gross weight 28kg/drum
Drum Size & Volume: I. D. 42cm × H52cm, 0.08 m³/ Drum