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Flumazenil 78755-81-4 High Quality Flumazenil
Our advantage--we provide EP6.0 Flumazenil and competitive price.
(1) 28 year experience in pharmaceutical industry
(2) ISO9001:2008 certificated company
(3) Fischer Chemicals AG China office
Basic information of Flumazenil EP6.0
1. CAS No.: 78755-81-4
2. Quality: EP6.0
3. Document: ISO
1. Specification of Flumazenil
Items | Specifications | Results |
Description | White or almost white, crystalline powder | Complies |
Solubility | Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in methanol. | Complies |
MP | 198℃ to 202 ℃ | 199.0℃~201.0℃ |
Appearance of solution | Solution S in clear (2.2.1) and not more intensely colored than reference solution BY7 (2.2.2,method II) | Complies |
Dimethylformamide diethyl acetal | ≤ 1% | Complies |
Related Substances | ||
Impurity B | ≤0.2% | 0.01% |
Any other impurity | ≤0.1% | 0.01% |
Total | ≤0.2% | 0.02% |
Loss on drying | ≤0.5% | 0.16% |
Residual Solvents | ||
Chloroform | ≤0.006% | Complies |
DMF | ≤0.088% | Complies |
Sulphated ash | ≤0.1% | 0.03% |
Assay | 98.0%~102.0% | 100.00% |
Conclusion | It conforms to the EP6.0 |
2. Use for Flumazenil
It has been used as an antidote in the treatment of benzodiazepine overdoses.
It is also sometimes used to reverse the effects of benzodiazepines after surgery in a manner similar tonaloxone's application to reverse the effect of opiates and opioids following surgery
It may also be effective in reducing excessive daytime sleepiness while improving vigilance in primaryhypersomnias, such as idiopathic hypersomnia.
It has also been used in hepatic encephalopathy, though results have been mixed.
3. Sinoway's advantage:
(1) ISO 9001:2008 certificated company
(2) 28 years in pharmaceutical industry
(3)China office of Fischer Chemicals AG (Switzerland)
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