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1 Kilogram |
FOB Price: USD 4500.0000 |
Glabridin Skin Lightening Skin Lightening Glabridin 5%-98%
Major function
Skin Lightening Glabridin 40% has anti-inflammatory,
Skin Lightening Glabridin 40%has anti-oxidation,
Skin Lightening Glabridin 40%has anti-aging,
Skin Lightening Glabridin 40%has UV abortion,
Skin Lightening Glabridin 40%has skin whitening,
Skin Lightening Glabridin 40%has spot removing.
Product character
Skin Lightening Glabridin 40%is the White crystalline Powder , dissolved in methanol, ethanol, propylalcohol,
propanediol and 1,3-butanediol.
Specfication:5%-98%
Application fields
Skin Lightening Glabridin 40%is widely used in cosmetic product as cream, paste, water solution and emulsion.
Item of test |
Standard |
Physical&chemical Control |
|
Assay(BY- HPLC)Content |
5.0%-98.0% |
Appearance |
Red-brown or White Powder |
Loss on drying |
5.0% |
Residue on ignition |
1.0% |
Heavy metals |
10ppm |
Arsenic salt |
2ppm |
Microbiological control |
|
Total of bacterium |
800CFU/g |
Yeast&Mold |
80CFU/g |
Salmonella |
Negative |
E.coli |
Negative |
Product description
Skin Lightening Glabridin 40% is an isoflavan from licorice root, which is a common component of herbal remedies used for treatment of menopausal symptoms. Past studies have shown that glabridin resulted in favorable outcome similar to 17β-estradiol (17β-E2), suggesting a possible role as an estrogen replacement therapy (ERT).
This study aims to evaluate the estrogenic effect of glabridin in an in-vitro endometrial cell line -Ishikawa cells via alkaline phosphatase (ALP) assay and ER-α-SRC-1-co-activator assay. Its effect on cell proliferation was also evaluated using Thiazoyl blue tetrazolium bromide (MTT) assay. The results showed that glabridin activated the ER-α-SRC-1-co-activator complex and displayed a dose-dependent increase in estrogenic activity supporting its use as an ERT. However, glabridin also induced an increase in cell proliferation.
When glabridin was treated together with 17β-E2, synergistic estrogenic effect was observed with a slight decrease in cell proliferation as compared to treatment by 17β-E2 alone. This suggest that the combination might be better suited for providing high estrogenic effects with lower incidences of endometrial cancer that is associated with 17β-E2.
Skin Lightening Glabridin 40% is a nature skin whitening agent extracted from special licorice and has ability of inhibit the activity of Tyrosinase,
Skin Lightening Glabridin 40% has ability to inhibit dopachrome tautomerase and activity of DHICA oxidation enzyme.
Skin Lightening Glabridin 40% is a green, highly efficient skin whitening agent and additive in cosmetic product, has similar ability as SOD to remove radicals and ability to antioxidant properties similar like Vitamin E.
Major function
Skin Lightening Glabridin 40% has anti-inflammatory,
Skin Lightening Glabridin 40%has anti-oxidation,
Skin Lightening Glabridin 40%has anti-aging,
Skin Lightening Glabridin 40%has UV abortion,
Skin Lightening Glabridin 40%has skin whitening,
Skin Lightening Glabridin 40%has spot removing.
Product character
Skin Lightening Glabridin 40%is the White crystalline Powder , dissolved in methanol, ethanol, propylalcohol,
propanediol and 1,3-butanediol.
Specfication:5%-98%
Application fields
Skin Lightening Glabridin 40%is widely used in cosmetic product as cream, paste, water solution and emulsion.
More Information
For further information about our company and products,
please welcome to log on to our official website: www.huataibio.com,
or directly contact us.
Griffin.zhang
Head Office :Room 11513, 15th Floor, No.5 Wenyi Road, Beilin Dist, Xi'an City Shaanxi province, China
Tel: +86-29-87862197
Fax: +86-29-87852512
Skype: griffon1124
Shaanxi Huatai Bio-fine Chemical Co.,Ltd.
CAS NO:59870-68-7
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