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Imatinib Mesylate 220127-57-1 Imatinib Mesylate hot supplier
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Product Name: Imatinib Mesylate
Cas No.: 220127-57-1
Molecular Formula: C30H35N7O4S
Molecular Weight: 589.71
TEST |
SPECIFICATION |
Appearance |
White or yellowishcrystalline powder, odorless or almost odorless |
Solubility |
Very easily soluble in water, soluble in methanol, almost insoluble in ethyl acetate |
Melting point |
Between 221-229°C |
Identification |
|
Chemical reaction |
Positive reaction |
IR |
IR spectrum of sample should be identical with that of reference standard |
Retention Time |
Retention time of the principal peak obtained from the test solution should be identical with that of the reference solution |
Related substances |
|
Carboxylic acid |
NMT 0.13% |
By-product I |
NMT 0.13% |
Single unspecified impurity |
NMT 0.1% |
Total impurities |
NMT 0.5% |
N-Methyl Piperazine and pyrilamine (contract analysis) |
|
N-Methyl Piperazine |
NMT 0.05% |
Pyrilamine |
NMT 0.0002% |
3-Acetylpyridine |
NMT 0.02% |
Dimethylamine |
NMT 0.05% |
Ethyl methanesulfonate(contract analysis) |
NMT 0.0001% |
Residue solvents |
|
Petroleum ether |
NMT 0.0029% |
Ethyl acetate |
NMT 0.5% |
Ethanol |
NMT 0.5% |
Pyridine |
NMT 0.02% |
Loss on drying |
NMT 1.0% |
Residue on ignition |
NMT 0.1% |
Heavy metals |
NMT 20ppm |
Chloride |
NMT 0.01% |
Assay |
98.0%~102.0%, C29H31N7OCH4SO3 |
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