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Alpha-GPC Choline Alfoscerate L-A-glycero phosphorylcholine
four specifications 50%(water-soluble;nondeliquescent) 85%(liquid) 99%(powder)
we can provide 50% nondeliquescent alpha-GPC, not caking, not deliquescent , we are the only supplier can provide such property GPC!
complete synthesis, so high purity, low endotoxin and low cost than partial synthesis
various applications : Soft capsule;Tablet.Oral liquid.functional drink
have a complete range of file system(Process validation;Cleaning validation;Test method validation;Stability test)
Alpha-GPC
Product name: Choline glycerophosphate, Choline Alfoscerate
Other name: Alpha GPC, L-ALPHA-Glycerophosphoryl choline;
(2S)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate; (2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate.
CAS : 28319-77-9
Formula: C8H20NO6P
Mol. Mass: 257.22
Appearance: off-white to white crystalline powder or colorless sticky liquid.
Assay: 99% or 85% or 50%
Package: 25kg/drum
What is Alpha GPC
Choline alfoscerate (also known as Alpha-GPC) is L-a-glyceryl phosphorylcholine (GPC), a key brain cell membrane phospholipid and cholinergic precursor. It is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources.
Choline alfoscerate is an important neurotransmitter and phospholipid precursor providing support for age-related decline in cognitive function, memory, and cerebrovascular health
What are the Benefits of taking Alpha GPC
Main functions :
GPC has been shown to:
Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer’s Disease. An Italian multicentre clinical trial on 2,044 patients suffering from stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance.
Other functions :
Research supports choline alfoscerate' s ability to support healthy brain function and the release of somatotrophin (hGH).
Another study has reported that 600mg Alpha-GPC taken 45 minutes prior to physical exercise is able to augment the exercise-induced growth hormone spike from 5.0+/-4.8ng/mL in placebo to 8.4+/-2.1 ng/mL with supplementation. The increase appeared to be significantly more than placebo when measured immediately and up to 15 minutes after exercise cessation, normalizing at 60 minutes
One study using Alpha-GPC at 1,000mg has reported that, in otherwise healthy men, an increase in plasma biomarker of lipolysis (the ketone bodies acetoacetate and 3-hydroxyacetate, as well as free fatty acids) was reported to occur 120 minutes after supplement ingestion
Supplemental of Alpha-GPC given 600mg Alpha-GPC prior to a power test (bench throws) reported a 14% power output improvement relative to placebo when taken 45 minutes prior to activity
Recommended dosage
A standard dosage of alpha-GPC is 300-600 mg, according to the most common label doses. This dose is in accordance with the study using alpha-GPC to enhance power output (600 mg) and the two studies noting an increase in growth hormone secretion, and is likely a good dose to take for athletes.
For the usage of alpha-GPC in attenuating symptoms of cognitive decline, almost all studies use a dosage of 1,200 mg daily, divided into three doses of 400 mg. It is unsure how lower doses would benefit cognition, but the 1,200 mg appears to be consistently associated with benefit.
Cima Science is an alternative and complementary ingredients and raw materials manufacturer of herbal/botanical extracts, nutritional supplement, food & beverage, pharmaceuticals ,cosmetic &Chemicals industries. Including related OEM service
As an innovator in the Chemical, biotechnological and phytochemical fields. Process development and product innovation form the focus of the ongoing R&D efforts in the company's research facilities which located in the Juye Shandong and Wuxi Jiangsu. And Cima Science has more than twenty scientists working full time to support these efforts. Laboratory and pilot scale production is performed at Cima's research facilities. and Also in JuYe, Shandong Province. Commercial scale production is carried out at four company-owned factories which handle product volumes ranging from a few hundred kilograms to several hundred tons.
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