Metronidazole 443-48-1 C6h9n3o3
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(ITEMS) |
(STANDARDS) |
(RESULTS) |
|
Appearance |
a white or yellowish crystalline powder |
COMPLY |
|
Solubility |
Slightly sobube in water,in acetone,in alcohol and in methylene,chloride,very slightly solube in ether |
COMPLY |
|
Identification a),b) |
c) infrared
|
c) COMPLY a) 160.8-161.7℃ b) 383 |
|
Loss on drying |
0.5% MAX |
0.15% |
|
Residue on ignition |
0.1% MAX |
0.04% |
|
Heavy Metal |
20PPM MAX |
<20PPM |
|
Particle size |
40-80 MESH |
COMPLY |
|
Residual solvents |
Methylene oxide(LOD 0.15ppm) Formic acid(LOD 124ppm) |
Not detected Not detected |
|
Appearance of solution |
SUSPENSION Ⅱ AND SOLUTION GY6 |
COMPLY |
|
Related substances:
|
1) Impurity |
0.1%MAX |
0.038% |
2) Total impurity |
0.2%MAX |
0.137% |
|
3) Disregard limited |
0.01% MAX |
PASS |
|
Assay |
99.0%-101.0% C6H9N3O3 |
99.73% C6H9N3O3 |
|
Conclusion: comply with the requirement of BP2012 standard. |
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