Falcarinol

Falcarinol

Falcarinol

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : L/C,T/T

Keywords

Falcarinol 21852-80-2 Carotatoxin

Quick Details

  • Appearance:white crystalline powder
  • Application:Biological effects[edit]It was shown that falcarinol acts as a covalent cannabinoid receptor type 1 inverse agonist and blocks the effect of anandamide in keratinocytes, leading to pro-allergic effect
  • PackAge:airtight foil bag in carton or drum
  • ProductionCapacity:1|Kilogram|Week
  • Storage:room temperature, cool, dry
  • Transportation:air/sea/courier

Superiority:

Falcarinol (carotatoxin) is a natural pesticide and fatty alcohol found in carrots (Daucus carota), red ginseng (Panax ginseng) and ivy. In carrots, it occurs in a concentration of approximately 2 mg/kg.[1][2] As a toxin, it protects roots from fungal diseases, such as liquorice rot that causes black spots on the roots during storage.

Details:

Falcarinol (carotatoxin) is a natural pesticide and fatty alcohol found in carrots (Daucus carota), red ginseng (Panax ginseng) and ivy. In carrots, it occurs in a concentration of approximately 2 mg/kg.[1][2] As a toxin, it protects roots from fungal diseases, such as liquorice rot that causes black spots on the roots during storage.

Chemistry

Falcarinol is a polyyne with two carbon-carbon triple bonds and two double bonds.[3] Falcarinol can cause allergic and irritant contact dermatitis.[4] It is structurally related to the oenanthotoxin and cicutoxin.

Biological effects

It was shown that falcarinol acts as a covalent cannabinoid receptor type 1 inverse agonist and blocks the effect of anandamide in keratinocytes, leading to pro-allergic effects in human skin.[5]

Preliminary research in animal models suggest that falcarinol may have a protective effect against certain types of cancer. Laboratory rats fed a diet containing raw carrots or isolated falcarinol were a third less likely to develop full-scale tumors induced by azoxymethane than those in a control group.[6]

Normal consumption of carrots doesn't cause any toxic effect in humans. However, when falcarinol is delivered in high doses to laboratory animals, it causes neurotoxical problems.[7]

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