Tenofovir

Details:

1. Name:tenofovir 2. Cas No:147127-20-6 3. MF:C9H14N5O4P 4. Use:anti-HIV 5. Appearance:white crystals 1. Name:tenofovir 2. Cas No:147127-20-6 3. MF:C9H14N5O4P 4. Use:anti-HIV 5. Appearance:white crystals 6. Indications: Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-na?ve and treatment-experienced adults. There are no study results demonstrating the effect of tenofovir on the clinical progression of HIV. It also has activity against wild-type and lamivudine-resistant HBV. Tenofovir disoproxil fumarate (TDF) Cas Number: 202138-50-9 Tenofovir; PMPA; R-PMPA Cas Number: 147127-20-6 Tenofovir is an anti-HIV drug approved by the FDA (In October of 2001) to be used in combination with other HIV fighting medications. Viread belongs to a new class of drugs called Nucleotide Reverse Transcriptase Inhibitors (NtRTI). These are related to Nucleoside Reverse Transcriptase Inhibitors (NRTI) like zidovudine (AZT, Retrovir). The body converts Viread into a chemical that prevent HIV from reproducing in uninfected cells, but it does not help cells that have already been infected with the virus. As people with HIV lose CD4 cells - one of the immune system's main defenses - they become more likely to get infections and illnesses. Currently available anti-HIV drugs like AZT need three separate chemical steps before they are active. Viread needs only two chemical reactions (phosphorylation) to occur before it can start working. Partly due to this unique chemical feature, Viread also carries a "negative charge", allowing it to stay in the cells where it is active for a longer period. As a result, Viread only needs to be taken once a day.1. Nametenofovir 2. Cas No147127-20-6 3. MFC9H14N5O4P 4. Useanti-HIV 5. Appearancewhite crystals 1-(6-Aminopurin-9-yl)1. N1. Name tenofovir disoproxil fumarate 2. CAS No 147127-20-6 3. MF C9H14N5O4P 4. Use anti-HIV 5. Appearance white CAS No 147127-20-6 MF C23H34N5O14PUse anti-HIV Appearance white crystals Characteristics almost white crystalline Melting point 113 to 118°C Rotation -13 to 18°C Loss on drying ≤5.0% Contains ≥99 to 101% Molecular weight 635.51CAS registry number 405165-61-9Appearance white crystalline powder or solid Purity NLT98%Specification enterprise standardMolecular structure       Product NameTenofovir disoproxil fumarateSynonyms  9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate     Molecular Formula  C19H30N5O10P.C4H4O4Molecular Weight635.51CAS Registry Number405165-61-9AppearanceWhite crystalline powder or solidPuirtyNLT98%SpecificationEnterprise Standard  Molecular Structure  Packing Factory   introduction Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naïve and treatment-experienced adults. There are no study results demonstrating the effect of tenofovir on the clinical progression of HIV. It also has activity against wild-type and lamivudine-resistant HBV.