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manufacturer supply Vinpocetine CAS:42971-09-5
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42971-09-5
Brief Introduction
Vinpocetine is a synthetic alkaloid derived from the periwinkle plant (specifically, synthesized from the molecule known as 'vincamine') that appears to have a track record of usage in European countries for the treatment of cognitive decline, stroke recovery, and epilepsy. Vinpocetine is also commonly used as a Nootropic compound in the hopes that it may promote memory formation.
Product: |
Vinpocetine |
CAS: |
42971-09-5 |
Molecular Structure |
|
EINECS |
256-028-0 |
Molecular formula: |
C22H26N2O2 |
Molecular weight: |
350.45 |
Physical Description: |
White or slightly yellow,crystalline powder |
Biological Source: |
Voacanga africana |
Melting Point: |
MP 147-153℃ |
Assay: |
Not less than 98.5% and not more than 101.5% |
Storage conditions: |
2-8°C refrigerated, sealed, avoid light |
The period of validity: |
2 years |
|
|
TEST |
STANDARD |
RESULTS |
Appearance |
White or slightly yellow,crystalline powder |
White crystalline |
Solubility |
Practically insoluble in water, soluble in methylene chloride,Slightly soluble in anhydrous ethanol |
Conforms |
Identification(IR) |
The spectrum must exhibit the maxima only at the same wave numbers as thai of the Vinpocetine CRS similarly prepared |
Conforms |
Specific Optical Rotation |
Between+127 º and +134 º |
+132.7 º |
Realated Substances |
|
|
Ethyl vincaminate(A) |
Not more than 0.6% |
Confroms |
Apovincamine(B) |
Not more than 0.5% |
Conforms |
Methoxyvinpocetine(C) |
Not more than 0.3% |
Not detected |
Dihydrovinpocetine(D) |
Not more than 0.5% |
Not detected |
Other single impurity |
Not more than 0.1% |
Conforms |
Total impurity |
Not more than 1.0% |
0.19% |
Loss on drying |
Not more than 0.5% |
0.04% |
Sulphated ash |
Not more than 0.1% |
0.07% |
Assay |
Not less than 98.5% and not more than 101.5% |
100.2% |
Function of Vinpocetine
1. Effects on brain circulation and oxygen utilization without changes in systemic circulation;
2. Increased tolerance of the brain to vascular hypoxia and ischemia;
3. Anticonvulsant activity;
4. Phosphodiesterase-1 inhibition;
5. Lowering of blood viscosity and inhibition of aggregation of thrombocytes
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