Noopept 157115-85-0 high purity low price factory

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 185.0000 -200.0000

1 Kilogram

FOB Price:USD 185.0000 -200.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Noopept factory 157115-85-0 low price 157115-85-0 high purity

Quick Details

Appearance:white crystalline powder
Application:1. Enhance memory 2. Treatment of Alzheimer's disease Noopept is prescribed in Russia and certain other eastern-european countries, though not in America.
PackAge:25kg/carton drum(32cm*58cm)or 1kg/foil bag(10cm*15cm) or by request of clients
ProductionCapacity:5000|Kilogram|Month
Storage:keep it away from heat and wet
Transportation:EMS,DHL,UPS , BY AIR , By sea or by your request

Superiority:

Noopept

N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity, indicating a potential application in the treatment of neurodegenerative diseases.It also demonstrates antioxidant and anti-inflammatory effects, which have been examined in the context of an anti-diabetic agent. This compound was recently identified in illegal designer herbal products distributed in Japan and is intended for research and forensic purposes only.

Details:

Nooglutil exhibits pharmacologically significant competition with a selective agonist of AMPA receptors ([G-3H]Ro 48-8587) for the receptor binding sites (with IC50 = 6.4 +/- 0.2 microM), while the competition of noopept for these receptor binding sites was lower by an order of magnitude (IC50 = 80 +/- 5.6 microM) [1]. GVS-111 significantly increased neuronal survival after H(2)O(2)-treatment displaying a dose-dependent neuroprotective activity from 10 nM to 100 microM, and an IC(50) value of 1.21+/-0.07 microM. GVS-111 inhibited the accumulation of intracellular free radicals and lipid peroxidation damage in neurons treated with H(2)O(2) or FeSO(4), suggesting an antioxidant mechanism of action

Alternate Name	1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester; or N-Phenylacetyl-L-prolylglycine ethyl ester; SGS-111; GVS 111
Appearance	White powder
CAS #	157115-85-0
Molecular Formula	C??H??N?O?
Molecular Weight	318.4
Purity	≥98% by TLC
Solubility	DMSO (25 mg/ml)
SMILES	CCOC(=O)CNC(=O)C1CCCN1C(=O)CC2=CC=CC=C2
InChi	InChI=1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1
InChi Key	PJNSMUBMSNAEEN-AWEZNQCLSA-N
PubChem CID	180496
MDL Number	MFCD00941121
Handling	Protect from air and light
Storage Conditions	-20°C
Shipping Conditions	Gel Pack