Superiority:
Kono chem is located in Xi'an, Shaanxi Province, equipped with a number of engineers in Pharmaceutical, Nutrition, Bioengineering, committed themselves to create products that meet customer requirements. At present, Kono's main products cover pharmaceutical, food, cosmetics, scientific research, optoelectronic industry and other fields, marketing in more than 50 countries in the world, mainly for the Daewoong, Takeda, CIPLA and other global well-known enterprises.
Kono's plant is located in the new district, Tongchuan city, Shaanxi province, covering an area of 312,000 square meters, with more than 35% scientific and technical personnel. The plant has two chemical fermentation workshops, one test reaction workshop and one provincial R & D center. Since the establishment of the company, Kono strictly manages its production in accordance with the demand of ISO9000、ISO14001 and other norms and has received the recognition from customers and authoritative laboratory audits all over the world.
Persisting to the principle of“Integrity and Diligence”, Kono is rising up with its hardworking employees and efficient research and development system and will engage itself to play an active role in the development of chemical industry together with domestic and foreign colleagues!
Details:
Name :Idebenone
Chemical name: 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone
Appearance:Orange needle-like crystals are obtained from petroleum ether,
Solubility: Easily soluble in chloroform, methanol or absolute ethanol, soluble in ethyl acetate, soluble in most organic solvents, hardly soluble in n-hexane, and almost insoluble in water.
Density: 1.08 g/cm3
Melting point: 46-55℃
Boiling point: 497.3ºC at 760 mmHg
Flash point: 170.1ºC
Efficacy
It can activate mitochondrial function, improve brain function metabolism and brain dysfunction, can increase the absorption of glucose in the brain, and promote the production of ATP; it can improve the metabolism of the neurotransmitter serotonin in the brain, and has an improving effect. The role of oxidation and scavenging free radicals.
Clinically, it is mainly used to treat central nervous system diseases related to oxidative compression, such as Parkinson’s disease, Alzheimer’s disease, multi-infarct dementia, cerebral anemia and brain failure, etc., and also used in Friedreich In the treatment of dysfunction, it can also be used in cosmetic formulations, which have cosmetic effects such as scavenging free radicals, inhibiting free radical peroxidation, inhibiting resonance, inhibiting DNA damage, photoprotection, and reducing pigmentation.
Test
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SPECIFICATION
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RESULTS
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Appearance
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Orange to yellow crystalline powder
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Complies
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Melting range
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52-55℃
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Complies
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Loss on drying
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≦0.1%
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0.02%
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Residue on lgnition
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≦0.1%
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0.02%
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Heavy Metals
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≤10ppm
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Complies
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Total impurities
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≦0.8%
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0.20%
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Assay (hplc)
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≧98.5%
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99.1%
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Residue solventies
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Hexane ≦0.029%
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0.006%
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Methanol ≦0.3%
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ND
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Toluene ≦0.89%
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0.0085%
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Conclusion
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Conform to the standard
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