Arthritis Onsenal Xilebao
Synonyms
Celebra
Celebrex
Onsenal
SC-58635
Xilebao
YM-177
Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2) (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). While it was initially hailed as a major therapeutic advance in treating inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial anti-inflammatory drugs, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events. Celecoxib also displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of its capacity to block COX-2.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View