Superiority:
Synonym:Januvia; Xelevia; Sitagliptan; Janumet
Application:A DPP-4 inhibitor
CAS Number:486460-32-6
Molecular Weight:407.31
Molecular Formula:C16H15F6N5OSitagliptin is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. This enzyme-inhibiting drug is to be used either alone or in combination with metformin or a thiazolidinedione for control of type 2 diabetes mellitus. The drug works to competitively inhibit a protein/enzyme, dipeptidyl peptidase 4 (DPP-4), that results in an increased amount of active incretins (GLP-1 and GIP), reduced amount of release of glucagon (diminishes its release) and increased release of insulin.