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Carperitide pharmaceutical peptide Peptide
Lab Supply Pharmaceutical Peptide Carperitide :
Carperitide Acetate | CAS 89213-87-6 | Brand: Filter |
MW:3080.4 | MSDS: Avaiable | |
MF : C127H203N45O39S3 | Sample: Avaiable | |
Category: Peptide Synthesis Reagents | Min order: 1 gram | |
Quality standard : Purity: 98%up | Place of Origin:China | |
Storage and Packing |
Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement. Storage:a cool(2~8 °C) & dry place protected from light, keep package close when not in use. |
|
Sequence | Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-IIe-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (SS :7-23) | |
Remark | Our products are limited to scientific research and production use only .Our products will not be sold to countires and regions under administrative and patent protections. |
Description :
Carperitide, a recombinant form of alpha-hANP, possesses potent diuretic, natriuretic, and vasodilatory activity, and inhibits the renin-aldosterone system and sympathetic nervous activity. However, its beneficial effects on ischemic myocardium have not been studied fully. We examined carperitide's effects on infarct size, hemodynamics, and arrhythmia frequency in anesthetized dogs (n = 20) subjected to a 90-min coronary artery occlusion/6-h reperfusion protocol. Intravenous infusion of carperitide (0.2 microg/kg/min) commenced 15 min after occlusion and continued during occlusion/reperfusion.
Ventricular fibrillation developed in two of 10 control versus three of 10 treated dogs (p = NS). Hemodynamics, collateral blood flow to the ischemic wall measured 10 min after occlusion, and extent of area at risk were comparable for the two groups. Infarct size/area at risk was smaller in treated than in control dogs (4.5 +/- 2.1% vs. 27.8 +/- 7.8%, respectively; p < 0.05).
During occlusion, carperitide tended to increase collateral blood flow (+39%) and significantly decreased left ventricular systolic pressure (-13%) and end-diastolic pressure (-40%) compared with baseline. In control dogs, collateral blood flow tended to decrease (-8.3%), whereas most hemodynamic parameters did not change significantly with respect to baseline.
The number of arrhythmias recorded during occlusion/reperfusion was similar in the two groups. Intravenous administration of carperitide limited infarct size, but did not reduce incidence of ventricular arrhythmias after 90-min coronary occlusion/6-h reperfusion in anesthetized dogs. Although the beneficial effects of carperitide may be attributable to concomitant changes in hemodynamics and collateral blood flow, the precise mechanisms require further investigation.
This is Linda from Zhengzhou Filter Biotechnology Co.,Ltd.We are the professional supplier of peptide products in China over 10 years. we have Professional Lab to confirm the Quality and Serive for all clients in long-term run cooperation.
Our Company as a Pharmaceutical Raw Material Manufacturer specialize in R&D the New Drugs and Producing the Generic Medicine:
Amino Acids&Vitamins
Pharmaceutical Polypeptide,
Comestic Polypeptide,
Veterinary Peptide and
Pharmaceutical APIs.
Due to of the high quality and good service, They have been exported more than 30 countries.
Sincerely hope to have a chance to cooperate with you.
Product Name | Thymosin a1 Acetate |
Appearance | White fine crystals |
Package & Storage |
Package: 25kg/drum or 25kg/cartol Storage: cool and dry well-closed container, keep away from moisture and strong direct sunlight |
Shelf Life | Two years under well stored |
ITEM | SPECIFICATION |
Appearance: | White crystalline Powder |
Assay: | ≥99.0% |
Heavy Metals | ≤10ppm |
Arsenic | ≤1ppm |
Lead | ≤3ppm |
Mercury | ≤0.1ppm |
Cadmium | ≤1ppm |
Total Plate Count | ≤1000cfu/g |
Yeast & Mold | ≤100cfu/g |
E.Coli | Negative |
Salmonella | Negative. |
Conclusion: The product conforms to the standard. |
Highly recommendation of Hyaluronic Acid |
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4.L-Arginine |
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7.BCAA |
8.Spirulina Powder &Chlorella Powder. |
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Peptide Categories
Packaging&Shipping.Our Lab
Contact information
Linda 008618203638264
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