Cosmetics peptide Pal-GQPR (Palmitoyl Tetrapeptide-3) CAS 57773-63-4

Details:

Description

Detail info :

Formula : C34H62N8O7

Molecular Weight:  694.910

Sequence (one-letter code): Palm-GQPR

Sequence (three-letter code): Palm-Gly-Gln-Pro-Arg-

N-Terminal: Palmitoyl

Description :

GenScript Palmitoyl Tetrapeptide-3 stimulates expression of GCP-2 (Granulocyte Chemotactic Protein), which is a chemotactic protein that can recruit cells involved in the preparation and cleansing of the site, to damaged areas. Palmitoyl Tetrapeptide-3 is also called Rigin. Rigin is a synthetic peptide that is a fragment of immunoglobulin G that has been combined with palmitic acid to make it more lipophillic and thus enhance its affinity towards human skin. Rigin is a peptide that mimics DHEA in the skin.

Palmitoyl pentapeptide-3 is available in an array of skin care creams, including Complexion MD Advanced Anti-Wrinkle Cream, the DERMADoctor Wrinkle Revenge Duo, and Estée Lauder Perfectionist Anti-Wrinkle Serum.  Savvy recessionistas will be happy to know that palmitoyl pentapeptide-3 is also included in the Olay ProX line.

Palmitoyl tetrapeptide-7 :

Palmitoyl tetrapeptide-7 is found in Peter Thomas Roth Unwrinkle Night.

Palmitoyl tetrapeptide-7 is the new name for palmitoyl tetrapeptide-3, not to be confused with palmitoylpentapeptide-3, described above.  Palmitoyl Tetrapeptide-7 reduces inflammatory cytokines, known as interleukins (Clinics in Dermatology, 1999).  By reducing inflammation, palmitoyl tetrapeptide-7 may potentially reduce the cumulative amount of damage that occurs following exposure to UV light, pollution, internal stress, and other pro-inflammatory factors.  Cells exposed to UV radiation and then treated with Palmitoyl Tetrapeptide-7 saw an 86% reduction of interleukin production.

There are very few studies that report the topical effects of palmitoyl tetrapeptide-7 on its own.  Despite this, it is included in a number of skin care creams, including Peter Thomas Roth Un-Wrinkle Night and Avon Anew Rejuvenating Night Cream.

Usage:

1.)  Use the right peptides.  Palmitoyl pentapeptide-3 and Matrixyl (which is actually palmitoyl tetrapeptide-7 + palmitoyl oligopeptide) have the most substantiated research backing their claims thus far.

2.)  Apply consistently.  Twice-daily use is great, but make sure to use it especially at night, to stimulate collagen production most effectively.

3.)  Be patient.  Most of these creams take at least six weeks to see a noticeable difference.