Ceftizoxime sodium injection supplier in China

Details:

1. Introduction of Diethyl fluoromalonate 

Diethyl fluoromalonate with the CAS registry number 68401-82-1, is also known as 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodiumsalt, (6R,7R)-. Its systematic name is sodium (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Its classification codes are: (1)Antibacterial; (2)Antibiotics; (3)Drug / Therapeutic Agent; (4)Reproductive Effect.

2. Basic Information of Diethyl fluoromalonate 

It is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.

1) Properties

Physical properties of Diethyl fluoromalonate is: (1)ACD/LogP: 0.59; (2)# of Rule of 5 Violations: 1; (3)#H bond acceptors: 10; (4)#H bond donors: 4; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 169.18 ?2.

2) Descriptors of Structure
You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].O=C2N1/C(=C\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)C([O-])=O
(2)Std. InChI: InChI=1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1
(3)Std. InChIKey: ADLFUPFRVXCDMO-LIGXYSTNSA-M

3) Toxicity

4) Side effects

Ceftizoxime may cause side effects. If you are administering ceftizoxime into a muscle, it may be mixed with lidocaine (Xylocaine) to reduce pain at the injection site. Tell your health care provider if any of these symptoms are severe or do not go away: stomach pain; upset stomach; vomiting.