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1. Introduction of Oxiracetam
PropertiesOxiracetam ,with the cas register number of 62613-82-5, is also called Oxiracetam [INN:BAN] ; 4-Hydroxy-2-oxo-1-pyrrolidineacetamide ; 4-Hydroxypiracetam ; Hydroxypiracetam ; Oxiracetamum ; 1-Pyrrolidineacetamide, 4-hydroxy-2-oxo- ; 4-Hydroxy-2-oxo-1-pyrrolidineacetamide .It can soluble in water.
2. Basic Information of Oxiracetam
1) Properties
XLogP3-AA: -2.2
H-Bond Donor: 2
H-Bond Acceptor: 3
Melting Point: 165-168 °C
Surface Tension: 69.2 dyne/cm
Density: 1.416 g/cm3
Flash Point: 252.9 °C
Enthalpy of Vaporization: 87.77 kJ/mol
Boiling Point: 494.6 °C at 760 mmHg
Vapour Pressure: 7.39E-12 mmHg at 25°C
Product Categories: Pharmaceutical material and intermeidates;APIs;API;(intermediate of oxiracetam)
2) Uses
Oxiracetam (CAS NO.62613-82-5) is a new psychotropic drug that has been shown to positively affect processes both in animals and in patients with impaired brain function.to promote smart medicine for the elderly brain mental dysfunction syndrome, mental disorders .
3) Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | > 5gm/kg (5000mg/kg) | Drugs of the Future. Vol. 5, Pg. 405, 1980. | |
dog | LD50 | oral | > 10gm/kg (10000mg/kg) | Drugs of the Future. Vol. 5, Pg. 405, 1980. | |
mouse | LD50 | intraperitoneal | > 10gm/kg (10000mg/kg) | Drugs of the Future. Vol. 5, Pg. 405, 1980. | |
mouse | LD50 | intravenous | > 10gm/kg (10000mg/kg) | Drugs of the Future. Vol. 5, Pg. 405, 1980. | |
rat | LD50 | intraperitoneal | > 10gm/kg (10000mg/kg) | Drugs of the Future. Vol. 5, Pg. 405, 1980. | |
rat | LD50 | intravenous | > 10gm/kg (10000mg/kg) | Drugs of the Future. Vol. 5, Pg. 405, 1980. |
4) Safety Profile
Hazard Codes: Xi
Risk Statements: 36/38
R36/38:Irritating to eyes and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: UX9656638
the substance is safe even when high doses are consumed for a long period of time after Several animal studies.
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