Dimethyl Sulfoxide DMSO Pharmaceutical Intermediates
Product Name: |
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CAS: |
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MF: |
C2H6OS |
MW: |
78.13 |
EINECS: |
200-664-3 |
Dimethyl sulfoxide Chemical Properties |
Melting point |
18.4 °C |
Boiling point |
189 °C(lit.) |
density |
1.100 g/mL at 20 °C |
vapor density |
2.7 (vs air) |
vapor pressure |
0.42 mm Hg ( 20 °C) |
FEMA |
3875 |
refractive index |
n20/D 1.479(lit.) |
Fp |
192 °F |
storage temp. |
Store at RT. |
form |
liquid (temperature dependent) |
color |
clear colorless |
FreezingPoint |
18.4℃ |
Sensitive |
Hygroscopic |
Merck |
14,3259 |
BRN |
506008 |
Stability: |
Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic. |
CAS DataBase Reference |
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NIST Chemistry Reference |
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EPA Substance Registry System |
Safety Information |
Hazard Codes |
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Risk Statements |
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Safety Statements |
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WGK Germany |
1 |
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RTECS |
PV6210000 |
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F |
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HS Code |
29309070 |
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Hazardous Substances Data |
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Chemical Properties |
It is colorless liquid, and is hygroscopic. It is almost odorless with a bitter taste. It can be dissolved in water, ethanol, acetone, ether, benzene and chloroform. |
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Usage |
DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS). |
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Usage |
Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers |
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Usage |
Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR. |
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Usage |
A polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. |
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Usage |
Suitable for HPLC, spectrophotometry, environmental testing |
Wuhan Zhonghua Yongye Chemical Co.,Ltd. was established in 2002. It is a professional chemical corporate enterprise which engage in R&D, manufacturing and selling the chemical raw materials and fine chemicals. Its subordinate company Wuhan XinYe Chemical Co.,Ltd mainly manufacture the Dyestuff Intermediate; And Wuhan Yongye Logistics provides our own hazardous chemicals transportation . It won the support from the large chemical enterprise since the establishment. The annual sales rises from several million to 100 million. In 2010, it invested 3 million to build 6000㎡chemical warehouse, which provide the better platform for the development. The annul sales is near to 0.2 billion(RMB) in 2015, and reached to 0.3 billion(RMB) in 2016.
As the business continues to develop and grow, registered “ Wuhan Creative Chemicals Co.,Ltd. “ for the import and export business. The registered capital is 60 million(RMB). The main product includes DMF(dimethyl formamide); DMSO(dimethyl sulfoxide), Acetic Acid, Maleic Anhydride, Dimethyl Carbonate, DEG(diethylene glycol), Acetic Anhydride, Toluene, etc.
Our tenet is “Quality and credit first, moderate price, delivery on time”. Welcome to contact us and establish the long term good cooperation with each other.
CERTIFICATE OF ANALYSIS
Product Name: Dimethyl sulfoxide/DMSO
CAS: 67-68-5 MF: C2H6OS
Appearance: Colorless liquid
Package: 225Kg/plastic drum(bucket)
INSPECTION ITEMS |
PRODUCT INDEX |
INSPECTION RESULT |
CONCLUSION |
Characters |
It is colorless liquid, and is hygroscopic. It is almost odorless with a bitter taste. It can be dissolved in water, ethanol, acetone, ether, benzene and chloroform. |
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DMSO CONTENT % |
≥ 99.90 |
99.95% |
Conform |
ACID VALUE |
≤ 0.03% |
0.01% |
Conform |
Water Content % |
≤ 0.10% |
0.01% |
Conform |
CRYSTALIAING POINT |
≥ 18.3° C |
18.40° C |
Conform |
TRANSMITTANCE |
≥ 96.0% |
100.3% |
Conform |
REFRACTIVE INDEX |
1.4775~1.4790% |
1.4785% |
Conform |
DENSITY (20 ℃) |
1.098-1.106 |
1.100 |
Conform |
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Conclusion: Conform |
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