Baclofen

Baclofen
Baclofen
Baclofen
Baclofen
Baclofen

Baclofen

Min.Order / FOB Price:Get Latest Price

50 Gram

Negotiable

  • Min.Order :50 Gram
  • Purity: min 99%
  • Payment Terms : L/C,T/T,

Keywords

4-Amino-3-(p-chlorophenyl)butyric acid Baclofen CAS No.1134-47-0

Quick Details

  • Appearance:odorless white to off-white crystalline powder.
  • Application:skeletal muscle relaxants and sedatives
  • PackAge:aluminum foil packing or Fiber Can
  • ProductionCapacity:3|Metric Ton|Month
  • Storage:keep it at cool dry ventilated place
  • Transportation:UN 2811 6.1/PG 3 Hazard Class 6.1(b) Packing Group III

Superiority:

Baclofen,skeletal muscle relaxants and sedatives

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Details:

Product Name: Baclofen                  CAS No.: 1134-47-0

MF: C10H12ClNO2                            EINECS No.: 214-486-9

Place of Origin:China (Mainland)    Type: Baclofen

Brand Name:KRCHEM                      Model :API

Purity: 99%

Appearance: Odorless or practically odorless white to off-white crystalline powder.

Shelf life: 2 Years

Packing: Drum, Plastic Container

Usage:Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord. Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s. Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury. In addition, the intrathecal injection therapy of the product in clinical application can further improve the clinical efficacy, and make it possible to adjust drugs dosage which stabilizes the treatment effect. For the past 10 years, the clinical application of central muscle relaxant baclofen has made significant progress, particularly in accumulating a lot of experiences in the neurological rehabilitation treatment of reducing muscular tension and pain alleviation treatment.

 

Description                                              

High quality baclofen
Apperance: white powder 
CAS 1134-47-0
Quality:USP standard
packing:25kgs/drum

Introduction                                             

Baclofen is one kind of white powder or white to very faintly yellow solid. The IUPAC Name of this chemical is 4-Amino-3-(4-chlorophenyl)butanoic acid. Its Classification Code is Central Nervous System Agents .

Usage                                                       

Baclofen can be used as Specific GABA-B receptor agonist. Muscle relaxant (skeletal). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.

COA                                                           

Items  Specifications  Results
 Appearance white crystalline hygroscopic powder  Conform
 Identification IR in accordance with USP RS Conform
Specific optical Rotation [α]    -29.0°∼-32°  -31.4°
 pH 5.5-9.5 7.2
Moisture content ≤4% 0.25%
 Residue on ignition ≤0.5% 0.03%
 Chloride  ≤0.4%

<0.4%

 Heavy metals <0.01% <0.001
 Limit of potassium ≤0.2% 0.00% 
 Limit of Sodium ≤0.1% 0.01%
 Assay 97.0% ∼103.0% 99.4%
 Residue solvents(ethanol)  ≤0.5% 0.07% 
 Cyanide Not be detected N.D.
 Conclusion The results complies with USP36.  

 

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