Neomycin Sulphate 1405-10-3 FradioMycin Sulfate
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CAS No.: 1405-10-3
Other Names: Neomycin sulfate
MF: C23H48N6O17S
EINECS No.: 215-773-1 Place of Origin: China (Mainland) Type: Antibiotic and Antimicrobial Agents
Grade Standard: Medicine Grade Usage: Animal Pharmaceutica
neomycin sulfate is a kind of aminoglycoside antibiotics. This product to staphylococcus aureus (methicillin sensitive strains), corynebacterium genus, e. coli, klebsiella bacteria genera, proteus and enterobacteriaceae bacteria have good antibacterial effect, for each group streptococcus, streptococcus pneumoniae, enterococcus is active. This article pseudomonas aeruginosa, oxygen resistance.Bacteria to streptomycin, kanamycin and neomycin, have a partial or total cross resistance between gentamycin.
Neomycin sulphate is a kind of aminoglycoside antibiotics.This product to staphylococcus aureus (methicillin sensitive strains), corynebacterium genus, e. coli, klebsiella bacteria genera, proteus and enterobacteriaceae bacteria have good antibacterial effect, for each group streptococcus, streptococcus pneumoniae, enterococcus is active.This article pseudomonas aeruginosa, oxygen resistance.Bacteria to streptomycin, kanamycin and neomycin, have a partial or total cross resistance between gentamycin.Neomycin systemic medication has significant nephrotoxicity and ototoxicity, is currently limited to oral or topical application.
Test Item |
Standard Specification |
Test Data |
Item Conclusion |
Identification |
a) TLC |
Complies |
Qualified |
b) Color reaction |
Complies |
||
c) Sulfate reaction |
Complies |
||
Infrared absorption |
According with IR reference spectrum |
Meets the requirement |
Qualified |
Loss on drying |
≤8.0% |
3.20% |
|
Qualified |
|||
|
5.0-7.5 |
6.6 |
|
PH |
Qualified |
||
|
≤0.05% |
0.03% |
|
Residue on ignition |
Not more than 0.05% of weight |
Qualified |
|
|
The solution is clear |
Clear |
Qualified |
Substances insoluble in sodium carbonate |
|||
|
0.5% max on USP sieve 180(um) |
Meets the requirement |
|
Partical size |
Qualified |
||
|
≤10ppm |
10ppm |
|
Heavy metals |
The limit is 10ug per g |
Qualified |
|
Assay |
Not less than 680 ug/mg |
692ug/mg |
|
Qualified |
|||
Conclusion |
The sample is in compliance with the BP2005.Result: [Meets] the requirement |
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