Sevelamer hydrochlo...

Sevelamer hydrochloride

Sevelamer hydrochloride

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1 Metric Ton

Negotiable

  • Min.Order :1 Metric Ton
  • Purity: 99.9%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram

Keywords

Sevelamer hydrochloride 152751-57-0 Sevelamer HCl

Quick Details

  • Appearance:White powder
  • Application:pharmacetical intermediates
  • PackAge:25kg/fiber drum, sealed package
  • ProductionCapacity:10|Metric Ton|Month
  • Storage:Sealed package
  • Transportation:Sealed package, keep away from light

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Details:

 

Product name: Sevelamer hydrochloride
Other Name: Renagel, Sevelamer Hcl 
CAS NO.: 152751-57-0
Standard: USP standard
MF: (C3H7N)m.(C3H5ClO)n.(HCl)x
Appearance: White crystalline powder.

Sevelamer hydrochloride is poly(allylamine hydrochloride) crosslinked with epichlorohydrin in which forty percent of the amines are protonated. It is known chemically as poly(allylamine-co-N,N'-diallyl-1,3-diamino2-hydroxypropane) hydrochloride. Sevelamer hydrochloride is hydrophilic, but insoluble in water. 

 

Tests

Results

Specifications

Appearance

Complies

White crystalline  powder

Identification

Complies

Reponds to the test for Chlorides

 

Complies

By IR, to match with the working standard

Loss on Drying

5.88%

≤8.0%

Residue on ignition

0.13%

≤0.2%

Heavy  metal

< 20 ppm

≤20 ppm

Solubility  test

Complies

Should be to match with the standard

Related substances

0.7ppm

Epoxy chloropropanols ≤1ppm

 

7.8ppm

Allylamine ≤10ppm

Residual solvents

0.01%

Methanol ≤0.3%

 

0.03%

Acetonitrile ≤0.041%

Binding of Phosphate

5.90mmol/g

5.2~7.5mmol/g

Conclusion: Conforms to internal specification

 

 

 

 

 

 

 

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