Chloramphenicol Chlomin 56-75-7
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Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, chloramphenicol is still widely used because it is exceedingly inexpensive and readily available.
Test Item |
Analysis Specification |
Result |
|
Description |
Fine white or grayish white or yellowish white needle-like crystals or Elongated plates
elonggat |
yellowish white needle-like crystals or Elongated plates
|
|
Identification |
positive |
postitive |
|
Melting point
|
149 ~ 153°C |
149.0~ 152.30°C |
|
Assay |
98.5 ~ 102% |
99.0% |
|
Loss on drying |
≤0.5% |
0.12% |
|
Residue on ignition |
≤0.1% |
0.09% |
|
PH |
5.0 ~ 7.5 |
5.68 |
|
Specific rotation heavy
|
+18.5 ~ +20 ° |
+18.8° |
|
Heavy metals
|
≤0.001% |
<0.001% |
|
Related substances |
The any secondary spot ≤0.5% total≤2% ≤0.1% |
<0.5% Total <2% |
|
Chloride |
≤0.005% |
<0.005% |
|
Crystallinity |
Meets the requirements |
Meets the requirements requiremenrequirements |
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