- Min.Order :1 Metric Ton
- Purity: 99.3%
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
Tacrolimus Tacrolimus Monohydrate 109581-93-3
Quick Details
- Appearance:white crystalline powder
- Application:Pharmaceutical intermediates
- PackAge:25kg/fiber drum, sealed package
- ProductionCapacity:10|Metric Ton|Month
- Storage:Seald package, keep away from light
- Transportation:Sealed package, keep away from light
Superiority:
1. Advanced facility and Equipment
2. Competent technical team
3 .Strong R & D support
4,high quality products with high stability
5, Competitive price
5.Customer tailored service
Details:
Introduction:
Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis. Tacrolimus is used to prevent rejection of organ transplants. Tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acute rejection after transplantation, but decreasing the toxin side effects.
Certificate of Analysis for Tacrolimus :
|
Tests |
Specifications |
Results |
|
Description |
A white or off-white crystalline powder |
Conform |
|
Identification |
1. IR (USP <197K>) |
Conform |
|
2. HPLC retention times |
Conform |
|
|
Water (USP <921> Method I) |
1.6 ~ 3.0% |
2.1% |
|
Residue on ignition (USP <281>) |
£ 0.2% |
0.08% |
|
Heavy metals (USP <231> II) |
£ 20 ppm |
< 20 ppm |
|
Related substances (In-house HPLC method) |
Ascomycin £ 0.8% |
0.064% |
|
Dihydrotacrolimus £ 0.6% |
0.089% |
|
|
Total impurities £ 1.5% |
0.15% |
|
|
Residual solvents (In-house method) |
Acetone £ 2000 ppm |
Not detected |
|
Ethanol £ 2000 ppm |
Not detected |
|
|
Assay (on anhydrous basis) |
98.0% ~ 102.0% |
100.0% |
|
Conclusion: Complied with In-House standard |
||
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