Nifuroxazide Pharmaceutical for Animal Health CAS 965-52-6

Details:

Description                                           

Product Name: Nifuroxazide
Synonyms: BENZOIC ACID, 4-HYDROXY-, [(5-NITRO-2-FURANYL)METHYLENE]HYDRAZIDE;5-NITRO-2-FURALDEHYDE P-HYDROXYBENZOYLHYDRAZONE;NIFUROXAZIDE;p-hydroxybenzoic acid (5-nitrofurfurylidene) hydrazide;(nitro-5’furfurylidene-2’)hydroxy-4benzhydrazide;4-hydroxy-benzoicaci((5-nitro-2-furanyl)methylene)hydrazide;diarlidan;dicoferin
CAS: 965-52-6
MF: C12H9N3O5
MW: 275.22
EINECS: 213-522-0

Purity:99%

Melting point:281-283°C

Introduction                                         

Nifuroxazide is a nitrofuran compound inhibitor of STAT transcription factor signaling. Nifuroxazide is described to block constitutive phosphorylation of STAT3 by reducing Jak kinase autophosphorylation, decreasing the viability of myeloma cells depending on constitutive STAT3 activity for survival while not affecting normal peripheral blood mononuclear cells. Nifuroxazide produces decreases in tyrosine phosphorylation of Jak2 and Tyk2, and showed no effects on EGF receptor tyrosine kinase or Src kinase, indicating a relative specificity of Nifuroxazide for Jak2 and Tyk2. Nifuroxazide shows no inhibition of Akt or MAPK phosphorylation.

Usage                                                    

1.Prevent and cure enteric disease and urinary diseases caused by E. coli,Salmonella, Pasteurella, 

Clostridium perfringens, proteusbacillus vulgaris , necrobacillus and staphylococci. Also, it has 

effective treatment for swine dysentery. 
2.As feed additive can promote the feed intake of animal.
3.Treat the intestinal disease and systemic disease in aquatic animal caused by infection of 

bacteria, Vibrio, fungi. Its drug effect is more highly than other antibiotics. 
4. Prevent and cure the coccidiosis, cecohepatitis and leucocytozoonosis caused by leucocytozoon

 Caulleryi.

COA