Antiepileptic Drugs Pregabalin Lyrica
Antiepileptic Drugs Pregabalin Raw Powder CAS: 148553-50-8
Description:
Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults.Some off-label uses of pregabalin include restless leg syndrome,prevention of migraines,anxiety disorders,and alcohol withdrawal.When used before surgery it does not appear to affect pain after surgery but may decrease the use of opioids.
Common side effects include: sleepiness, confusion, trouble with memory, poor motor coordination, dry mouth, problem with vision, and weight gain.Potentially serious side effects include angioedema, drug misuse, and an increased suicide risk.When pregabalin is taken at high doses over a long period of time, addiction may occur, but if taken at usual doses the risk of addiction is low.Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels.
Parke-Davis developed pregabalin as a successor to gabapentin and was brought to market by Pfizer after the company acquired Warner-Lambert.There is to be no generic version available in the United States until 2018.A generic version is available in Canada, the United Kingdom, Australia and Germany. In the US it costs about 300-400 USD per month.Pregabalin is a Schedule V controlled substance under the Controlled Substances Act of 1970 (CSA).
Basic information:
Chemical name: Pregabalin
MF: C8H17NO2
MW: 159.23
CAS: 148553-50-8
Appearance: White powder
Purity: over 99%
COA:
Product name | Pregabalin | ||
CAS No. | 148553-50-8 | Outer Packing | 25KG/Cardboard Drum |
Production date | 2017.6.17 | Shelf life | 2 years |
Standard adopted | company standard | ||
Items of analysis | Specification | Results | |
Loss on drying |
≤0.5% |
0.21% |
|
Specific Rotation |
+10.0°~+13.0° |
+10.8° |
|
Related Substances | Any single impurity ≤0.1% otal impurity ≤0.8% |
0.05% 0.10% |
|
Purity By HPLC R-isomer |
≤0.15% |
0.10 |
|
Residue on ignition |
≤0.1% |
0.05% |
|
Heavy metals |
≤10ppm |
Complies | |
Chlorides |
≤0.05% |
Complies | |
Assay |
98%~102.0% |
99.8% |
|
Conclusion | Qualified |
What is Pregabalin and what is it used for
Pregabalin is used to treat some types of persistent pain. It is especially good for nerve pain, such as burning, shooting or stabbing pain. Pregabalin belongs to a group of medicines called anticonvulsants, which are also used to treat epilepsy.
Pregabalin works by changing the way that nerves send messages to your brain. If the messages are reduced, then the pain will be reduced.
CAS NO:1134-47-0
CAS NO:129499-78-1
CAS NO:66981-73-5
CAS NO:148553-50-8
CAS NO:
CAS NO:147403-03-0
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View