Prednisolone Acetate Prednisolone-21-acetate 52-21-1
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ITEMS | SPECIFICATIONS | RESULTS |
CHARACTER | WHITE OR ALMOST WHITE CRYSTALLINE POWDER | ALMOST WHITE CRYSTALLINE POWDER |
SPECIFIC ROTATION | +96°~+102° | +98.6° |
IDENTIFICATION | A: COMPLIES BY IR | CONFORMS |
B: COMPLIES BY TLC | CONFORMS | |
RELATED SUBSTANCES | INDIVIDUAL IMPURITY IS NOT MORE THAN 1.0% | 0.59% |
NOT MORE THAN ONE IMPURITY IS GREATER THAN 0.5% | 1 | |
TOTAL IMPURITIES NOT MORE THAN 2.0% | 0.93% | |
LOSS ON DRYING | NOT MORE THAN 1.0% | 0.10% |
ASSAY | IT SHOULD CONTAIN 97.0% TO 103.0% OF C21H28O5 CALCULATED ON DRIED BASIS | 98.80% |
CONCLUSION | THE RESULTS CAN CONFORMS WITH THE EP7/BP2011 |
Prednisolone Usage
It belongs to adrenocorticotropic hormone medicines, has anti-inflammatory, anti-allergic, anti-rheumatism, immunosuppressive effects.
1) It's use for the treatment of a wide range of inflammatory and auto-immune conditions
2) Such as asthma, uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, temporal arteritis and Crohn's disease, Bell's palsy, multiple sclerosis
3) Cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, and dermatomyositis
4) It is also used for treatment of sarcoidosis, though the mechanisum is unknown
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