Carmustine 154-93-8 Becenun
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Product Name carmustine
Molecular Formula C5H9Cl2N3O2
Molecular Weight 214.0499
CAS Registry Number 154-93-8
EINECS 205-838-2
Density 1.46g/cm3
Melting point 30°C
Refractive index 1.548
Water solubility <0.1 g/100 mL at 18°C
Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a medication used mainly for chemotherapy and sometimes for immunosuppression before organ transplantation. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent. As a dialkylating agent, BCNU is able to form interstrand crosslinks in DNA, which prevents DNA replication and DNA transcription.
Carmustine for injection was earlier marketed under the name BiCNU by Bristol-Myers Squibb and now by Emcure Pharmaceuticals. In India it is sold under various brand names, including Consium.
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