72956-09-3 Carvedilol Carvedilolum
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both block the α1. Carvedilol is an inhibitor of α1B-AR, β1-AR, β2-AR and α1D-AR.
Items |
Specification |
Result |
Appearance |
White or almost white crystalline powder |
White crystalline powder |
Solubility |
Practically insoluble in water,slightly soluble in alcohol,practically insoluble in dilute acids |
Conforms |
Identification |
IR Method |
IR Method |
Loss on drying |
≤0.5% |
0.13% |
Sulphated ash |
≤0.1% |
0.04% |
Related substance Total impurity Impurity A Impurity C Any other impurity |
≤0.5% ≤0.2% ≤0.02% ≤0.1% |
0.16% Conforms Conforms Conforms |
Heavy metals |
≤10ppm |
Conforms |
Residue toluol |
≤890ppm |
Not detected |
Residue acetone |
≤5000ppm |
Not detected |
Residue ethyl acetate |
≤5000ppm |
619ppm |
Assay |
99.0 ~ 101.0% |
99.80% |
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