FLUOCINONIDE 356-12-7 Fluocinolone Acetonide Acetate
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Fluocinolone acetonide is for external used only applies to glucocorticoid effective skin diseases, such as contact dermatitis and atopic dermatitis, seborrheic dermatitis, eczema, itchy skin disease, psoriasis, neurodermatitis, pruritus and noninfectious inflammatory skin disease.
Item
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Requirements
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Test Results
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Appearance
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White or almost white crystalline powder
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White crystalline powder
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Identification
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A Infrared absorption spectrophotometry
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A compliance
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B Examine the chromatograms obtained in the test
for related substances
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B compliance
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Specific optical Rotation
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+100°~+104°
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+101°
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Related substance
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||
Any impurity
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≤1%
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0.0027
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Not more than 1 impurity
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≤0.5%
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0.0023
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Total impurity
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≤2.5%
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0.009
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Assay
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97.0%~103.0%, calculated on the dried basis.
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0.999
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Particle size
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0~10μm
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0.6
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10~20μm
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0.3
|
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20~30μm
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0.1
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Conclusion
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Confirm with the specification
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