6-(trifluoromethyl)-1h-pyridin-2-one

Details:

Description:

2-hydroxy-6-trifluoromethyl pyridine appears as a white or off-white solid powder at room temperature and pressure. It is a commercial organic synth. Literature search results found that it often appears as its tautomerone ketone, rather than as a pyridine hydroxyl group. The solubility in ether solvents is general, and the solubility in water is poor. It can be used as an intermediate in organic synthesis.

Use:

2-hydroxy-6-trifluoromethyl pyridine is a common intermediate in organic synthesis, which is often used in its enol form to participate in the subsequent conversion, but it can also be protected by iodomethane to obtain a product of hydroxyl protected by methyl Chemicalbook group, which can retain the structure of the pyridine ring. In addition, perhaps also because of the enol-like structure, the pyridine ring can be hydrogenated under the catalysis of platinum dioxide to obtain lactam products.

Synthesis method:

For the synthesis of 2-hydroxy-6-trifluoromethyl pyridine, the conventional synthesis method starts from 2-chloro-6-trifluoromethyl pyridine, and obtains the target product by replacing chlorine into hydroxyl, but this process needs to be carried out under high temperature and strong alkali conditions. In addition, it has been reported that trifluoromethyl pyridine products can be obtained by fluorination of carboxyl groups.

Boiling Point	223.7±40.0 °C
Density	1.398±0.06 g/cm3
Storage Condition	Sealed in dry,Room Temperature
Solubility	Soluble in chloroform (a little), methanol (a little)
pKa	8.03±0.10

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

1:Safe shipping (TNT;EMS;FEDEX;DHL;UPS;EUB)

2:Safe payment(Btc;MoneyGram;WU)

3:Safe packing (Paraffin coating; Double aluminum foil bag; Vacuum packaging)

4:Fast delivery (3-10 DAYS fast home delivery service )

5:Best quality (Without any doping, all products are pure)

6:Safety guarantee (we do this business long time ,we know how to disguise let the product through customs)

8:New international transportation system(Pls see the pic,The transportation line reaches every corner of the world)

9:Huge Supply(We have many raw materials and processing centers,Each day can provide dozens of kilogram-hundreds of kilograms of different products.)

10:Low Price(All the products are factory prices it can let you have a bigger profit margin)

 

 

1.lowest price 

2.good service

3.best quality 

4.rich experience 

5.support sample

Details

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

1:Safe shipping (TNT;EMS;FEDEX;DHL;UPS;EUB)

2:Safe payment(Btc;MoneyGram;WU)

3:Safe packing (Paraffin coating; Double aluminum foil bag; Vacuum packaging)

4:Fast delivery (3-10 DAYS fast home delivery service )

5:Best quality (Without any doping, all products are pure)

6:Safety guarantee (we do this business long time ,we know how to disguise let the product through customs)

8:New international transportation system(Pls see the pic,The transportation line reaches every corner of the world)

9:Huge Supply(We have many raw materials and processing centers,Each day can provide dozens of kilogram-hundreds of kilograms of different products.)

10:Low Price(All the products are factory prices it can let you have a bigger profit margin)

Our distribution capabilities include:
● Flexible deliveries, intelligent solutions
● Anything from bulk shipments of thousands of tonnes down to the smallest shipment of packed goods and even samples.
● Bulk – storage and transport of powders and liquids – movement of goods in ships – powders and bulk liquids
● Pharma, feed and food storage to accredited standards
● Segregated materials by business unit and hazard classification
● Temperature controlled storage and transport
● Effective cost control
● Re-packing, drum filling, bagging, ripping and tipping
● Customer delivery KPI's on delivery fulfillment performance

e