CasNo.107868-30-4,CAS 107868-30-4 Anti Breast Cancer Powder Exemestane Aromasin,(107868-30-4) Suppliers

1 Kilogram	Negotiable

Min.Order :1 Kilogram
Purity: 99%
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Keywords

Exemestane Aromasin Exemestane Aromasin

Quick Details

Appearance:White crystalline powder
Application:CAS 107868-30-4 Anti Breast Cancer Powder Exemestane Aromasin
PackAge:(1). 1-10kg / foil bag (2). 25kg / drum (3). 1-50kg / barrel (4). By request of clients
ProductionCapacity:1000|Kilogram|Month
Storage:Store in cool & dry place
Transportation:1.Air Courier Express Door to Door Service DHL / TNT / FEDEX / UPS / EMS 2.Normal Air 3.Normal Sea

Superiority:

Exemestane Acatate Basic Info.

Other name: 6-Methylenandrosta-1, 4-diene-3, 17-dione; 10, 13-Dimethyl-6-methylidene-7, 8, 9, 10, 11, 12, 13, 14, 15, 16-decahydrocyclopenta[a]phenanthrene-

MF: C20H24O2

MW: 296.4034

CAS: 107868-30-4

Density: 1.13G/cm3

Melting point: 155.13° C

Boiling point: 453.7° C at 760 mmHg

Refractive index: 1.572

Flash point: 169° C

Vapour Pressur: 2.02E-08mmHg at 25° C

Appearance: White crystalline powder

Assay: 99% min

Melting point: 191-198 C

Exemestanne acetate Function:

Aromasin (Exemestanne acetate) is one of those weird compounds that nobody really knows what to do with. It's a third generation Aromatase Inhibitor (AI) just like Arimidex () and Femera ().

the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.

1. Aromasin is one of the most powerful estrogen suppressing compounds.

2. Aromasin is one of the best compounds to lower the aromatizing effect of steroids.

3. Aromasin is available for body builders taking anabolic steroids.

4.It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.

5.Aromasin is also a kind of .antineoplastic (hormonal) raw materials.

Details:

Exemestane Basic information

Indications and Usage Pharmacokinetics Drug interactions Side effects Clinical Research Contradictions Warnings and precautions

Product Name:	Exemestane
Synonyms:	(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestane (USP);ExeMestane(AroMasin);1,4-Androstadien-3,17-dione-6-Methylene-d2;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971
CAS:	107868-30-4
MF:	C20H24O2
MW:	296.4
EINECS:	1592732-453-0
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pfizer compounds;Steroid and Hormone;API;Anti-cancer&immunity;Inhibitors;Active Pharmaceutical Ingredients;chiral;Antineoplastic (Hormonal)
Mol File:	107868-30-4.mol

Exemestane Chemical Properties

Melting point	155.13°C
storage temp.	Store at -20°C
solubility	DMSO: ≥20mg/mL
color	white to off-white
InChIKey	BFYIZQONLCFLEV-DAELLWKTSA-N
CAS DataBase Reference	107868-30-4(CAS DataBase Reference)

This drug has no noticeable effect on adrenal corticosteroids biosynthesis. Even when its concentration is over 600 times the concentration required to inhibit aromatase, it still has no noticeable effect the other enzymes in the corticosteroid production pathway.
This drug is absorbed quickly when taken orally and will affect food absorption. Its oral bioavailability is 42%. Postmenopausal women have a higher absorption rate than healthy test subjects. Patients reach peak blood concentration 2-4 hours after intake, and the peak lasts for an average of 1.2 hours, which is 2.9 hours shorter than healthy subjects. It mainly binds to Α1-acid glycoprotein and protein, and its overall binding rate to protein is 90%. It is mainly metabolized by the liver, the metabolite is inactive 17-Hydrecoxetron, and its clearing half-life is 24 hours. It is mostly excreted through urine and feces, which both account for 42% of the consumed amount.

1. Air Courier Express Door to Door Service （DHL / TNT / FEDEX / UPS / EMS）

2. Normal Air

3. Normal Sea

Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and APIs, Raw Steroid, Hormone products and other raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.