99% pure high quali...

99% pure high quality Anti-inflammatory analgesic drugs Indometacin

99% pure high quality Anti-inflammatory analgesic drugs Indometacin

Min.Order / FOB Price:Get Latest Price

100 Gram

Negotiable

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : T/T,

Keywords

Indometacin Indometacin powder CAS 53-86-1

Quick Details

  • Appearance:white powder
  • Application:Anti-inflammatory
  • PackAge:aluminum foil bag, drum
  • ProductionCapacity:500|Kilogram|Month
  • Storage:cool and dry place
  • Transportation:email: wonda-chem@outlook.com

Superiority:

1.high quality:

quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.

2.reasonable price:

we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.

3.low moq:

no worry about the low moq, our moq is 1 gram or even lower.

4.good service.

fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.

5. fast shipping and secure courier.

we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.

 

 

Details:

Product Description

 

Indomethacin, an antiinflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis. Other studies show indomethacin to stabilize cholesterol-dependent nanoclusters and enhance phase separation in biological membranes, which could consequentially effect plasma membrane assembled cell signaling cascades. Indomethacin is an activator of PPAR α.

 

 

Specification

 

 

Product Name

Indomethacin

MFG. Date

Dec.12.2015

Batch NO.

HS13-068

EXP. Date

Dec.11.2018

Batch quantity

300kg

Analysis Date

Dec.18.2015

Standard

BP2005

Items

Specification

Results

Characters

White crystalline powder ,parctically   insoluble in water, sparingly soluble in alcohol

Conforms

Identification

 

 

A.Melting point

158-162°C

158.5-160.0°C

B.Absorption at 318nm

170-190

185.19

C.

Conforms to the requirement

Conforms

D.

Conforms to the requirement

Conforms

E.

Conforms to the requirement

Conforms

Related substances(TLC)

Not more than 0.5%

<0.5%

Heavy metals

Not more than 20ppm

<20ppm

Loss on drying

Not more than 0.5%

0.13%

Sulphated Ash

Not more than 0.1%

0.07%

Assay

98.5%-100.5%

99.8%

Conclusion:Complies with EP7

 

Function and Application

 

Indometacin (INN and BAN) or indomethacin (AAN, USAN and former BAN) is a non-steroidal anti-inflammatory drug(NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling. It works by inhibiting the production of prostaglandins, molecules known to cause these symptoms.

It is marketed under more than twelve different trade names.

 

 

Packing and shipping

 

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