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1 Gram |
Negotiable |
Letrozole Letrozole Letrozole
Product Description
Letrozole is an oral inhibitor for the treatment of hormonally-responsive breast cancer after surgery.
Letrozole prevents the aromatase from producing estrogens by competitive, reversible binding to the heme of its cytochrome p450 unit, the action is specific,and letrozol does not reduce production of mineralo-or corticoids.
Function and Application
Pyrrole type aromatization enzyme inhibitors. Used in the treatment of breast cancer.
Specification
Tests |
Specifications |
Results |
Appearance |
White or off-white crystaline powder |
White Crystalline powder |
Solubility
|
Soluble in Chloroform; Soluble in ethanol when heated |
Conform |
ldentification |
(1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm |
Conform Conform |
(2)Infrared spectrum should be in accordance the dominant peak of contrast |
In accordance with the dominant peak of contrast |
|
Melting points |
182°C-184°C |
182°C |
Related substances |
≤0.5% |
0.3% |
Single impurity |
≤0.3% |
0.2% |
Loss on drying |
≤1.0% |
0.8% |
[Assay]C17H11N5 (On anhydrous basis) |
≥98.0% |
99.2% |
Conclusion |
Conforms Specifications of Enterprise Standard. |
Packing and shipping
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