Zonisamide// Antiepileptic and anticonvulsant drugs

Details:

Introduction:

Name:Antiepileptic
CAS NO. :68291-97-4
Molecular Formula:C8H8N2O3S
Molecular Weight:212.23
EINEC:200-659-6
Melting Point :275°C 
Purity:99% Min

Zonisamide is a new generation of sulfonamide anticonvulsant that is primarily used as supplemental therapy in treatment of partial seizures in combination with other antiepileptic medications. Besides, it is approved to be applied as an adjunctive therapy in adults suffering from infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic, and generalized tonic clonic seizure. Recent studies have proved that zonisamide can acts as a migraine preventative medication and is effective in several cases of neuropathic pain. In an open-label trial, zonisamide shows positive effects on attenuating the symptoms of tardive dyskinesia. 

Function&Application:

1.anticonvulsant;carbonic anhydrase inhibitor, repetitive firing of voltage-gated sodium channels and reduction of T-type calcium channel currents blocker

2.Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with The compound is under investigation for potential therapeutic use as

3.an antiepileptic drug. Anticonvulsant.

4.muscarinic antagonist used as an antispasmodic

5.For use as adjunctive treatment of partial seizures in adults with epilepsy.

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