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10 Gram |
Negotiable |
Prednisolone base Prednisolone cas 50-24-8
1.high quality:
quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.
2.reasonable price:
we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.
3.low moq:
no worry about the low moq, our moq is 1 gram or even lower.
4.good service.
fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.
5. fast shipping and secure courier.
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Description
Name:prednisolone
Chemical name:11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione
CAS NO.: 50-24-8
EINECS:200-021-7
Chemical Structure
Molecular formula:C21H28O5
Molecular Weight:360.45
Standard:USP32
Functuon
[1]it's use for the treatment of a wide range of inflammatory and auto-immune conditions
[2]such as asthma,uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, temporal arteritis and Crohn's disease, Bell's palsy, multiple sclerosis
[3] cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, and dermatomyositis.
Application
Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, chloramphenicol is still widely used because it is exceedingly inexpensive and readily available.
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and a plastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
Item |
Specification |
Character |
White or almost white crystalline powder |
Specific rotation |
+96° TO +102° |
Identification |
A.complies by IR B.Complies by TLC |
Related substances |
Not more than one impurity between 0.5% TO 1.0% Total impurity not more than 2.0% |
Loss on drying |
Not more than 1.0% |
Particle size |
It should be 90% below μm |
Assay |
It should contain 97.0 to 103.0% of C21H28O5 calculated on dried basis |
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